TWIST1 transcriptionally regulates glycolytic genes to promote the Warburg metabolism in pancreatic cancer.
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DOI: 10.1016/j.yexcr.2019.111713
Abstract: Reprogrammed glucose metabolism is essential for tumor initiation and development, especially for pancreatic ductal adenocarcinoma (PDAC). Most cancer cells rely on aerobic glycolysis, a phenomenon termed "the Warburg effect", to support uncontrolled proliferation and evade… read more here.
Keywords: pdac; metabolism; twist1; warburg metabolism ... See more keywords