Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.0652
Abstract: Importance Left ventricular (LV) thrombi can arise in patients with ischemic and nonischemic cardiomyopathies. Anticoagulation is thought to reduce the risk of stroke or systemic embolism (SSE), but there are no high-quality data on the… read more here.
Keywords: use; warfarin; treatment; ventricular thrombi ... See more keywords
Efficacy and safety of dabigatran, rivaroxaban, and warfarin for stroke prevention in Chinese patients with atrial fibrillation: the Hong Kong Atrial Fibrillation Project
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DOI: 10.1002/clc.22649
Abstract: Little is known about the comparative effectiveness and safety of non–vitamin K antagonist oral anticoagulants (NOAC) compared to warfarin in Chinese atrial fibrillation (AF) patients. Our aim was to compare the ischemic stroke risk reduction… read more here.
Keywords: atrial fibrillation; fibrillation; warfarin; safety ... See more keywords
A potential drug interaction between Favipiravir and Warfarin in patients with COVID‐19: A real‐world observational study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacology"
DOI: 10.1002/jcph.2161
Abstract: Favipiravir is one of the most used antiviral agents for the treatment of coronavirus disease 2019 infection in many countries, including Thailand. This study aimed to investigate the effect of favipiravir‐warfarin interaction in terms of… read more here.
Keywords: interaction; favipiravir warfarin; study; warfarin ... See more keywords
Methodological challenges in assessment of current use of warfarin among patients with atrial fibrillation using dispensation data from administrative health care databases
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DOI: 10.1002/pds.4570
Abstract: Algorithms to define current exposure to warfarin using administrative data may be imprecise. Study objectives were to characterize dispensation patterns, to measure gaps between expected and observed refill dates for warfarin and direct oral anticoagulants… read more here.
Keywords: dispensation; warfarin; challenges assessment; assessment current ... See more keywords
Anticoagulant plus antiplatelet therapy for atrial fibrillation
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DOI: 10.1007/s00059-018-4747-6
Abstract: BackgroundEmerging evidence indicates combination therapy with anticoagulants and antiplatelet agents for atrial fibrillation (AF) will be increasingly required. Numerous studies compare the efficacy and cost-effectiveness of anticoagulation alone in AF, i. e., non-vitamin K oral anticoagulants (NOACs)… read more here.
Keywords: die; icer; warfarin; der ... See more keywords
A case series of the rifampin-warfarin drug interaction: focus on practical warfarin management.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of clinical pharmacology"
DOI: 10.1007/s00228-020-03057-x
Abstract: PURPOSE To provide practical guidance by providing weekly descriptions of warfarin requirements for the onset and offset of the rifampin-warfarin interaction. METHODS A retrospective chart review within an outpatient Anticoagulation Clinic (AC). Patients were eligible… read more here.
Keywords: week; warfarin; interaction; rifampin ... See more keywords
Major bleeding in a patient with warfarin-hypersensitive and factor IX propeptide variant, p.Ala37Thr, who was treated with a direct oral anti-Xa inhibitor
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DOI: 10.1007/s00277-018-3398-2
Abstract: Dear Editor, A variant of coagulation factor IX (FIX) is usually associated with hemophilia B, which causes severe bleeding, a prolonged activated partial prothrombin time (APTT) and markedly decreased FIX activity with a family history… read more here.
Keywords: warfarin; fix; anti; thrombosis ... See more keywords
Sublethal dose of warfarin induction promotes the accumulation of warfarin resistance in susceptible Norway rats
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DOI: 10.1007/s10340-020-01299-3
Abstract: Resistance to anticoagulant rodenticides in Norway rats has been primarily explained by selection on the mutations in the vitamin K epoxide reductase complex subunit 1 (Vkorc1) gene. Whether warfarin resistance can be induced independent of… read more here.
Keywords: warfarin induction; warfarin; warfarin resistance; resistance ... See more keywords
The influence of fibrate initiation on INR and warfarin dose in patients receiving chronic warfarin therapy
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DOI: 10.1007/s11239-018-1664-8
Abstract: Several drug interaction compendia report a risk of warfarin potentiation after initiation of a fibrate; however, the evidence of this interaction is limited. The objective of this study was to evaluate warfarin dose and international… read more here.
Keywords: initiation; receiving chronic; warfarin; patients receiving ... See more keywords
Fatal warfarin-associated intracranial hemorrhage in atrial fibrillation inpatients
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DOI: 10.1007/s11239-018-1767-2
Abstract: Ischemic stroke and major bleeding, mostly due to intracranial hemorrhage (ICH), cause about the same rates of death in pivotal randomized trials of direct oral anticoagulants (DOACs) versus warfarin for stroke prevention in atrial fibrillation… read more here.
Keywords: atrial fibrillation; warfarin; intracranial hemorrhage; fatal ich ... See more keywords
Comparative clinical outcomes between direct oral anticoagulants and warfarin among elderly patients with non-valvular atrial fibrillation in the CMS medicare population
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DOI: 10.1007/s11239-019-01838-5
Abstract: Atrial fibrillation (AF) prevalence increases with age; > 80% of US adults with AF are aged ≥ 65 years. Compare the risk of stroke/systemic embolism (SE), major bleeding (MB), net clinical outcome (NCO), and major adverse cardiac events… read more here.
Keywords: atrial fibrillation; risk; warfarin; lower risk ... See more keywords