A case series of the rifampin-warfarin drug interaction: focus on practical warfarin management.
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DOI: 10.1007/s00228-020-03057-x
Abstract: PURPOSE To provide practical guidance by providing weekly descriptions of warfarin requirements for the onset and offset of the rifampin-warfarin interaction. METHODS A retrospective chart review within an outpatient Anticoagulation Clinic (AC). Patients were eligible… read more here.
Keywords: week; warfarin; interaction; rifampin ... See more keywords
The influence of fibrate initiation on INR and warfarin dose in patients receiving chronic warfarin therapy
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DOI: 10.1007/s11239-018-1664-8
Abstract: Several drug interaction compendia report a risk of warfarin potentiation after initiation of a fibrate; however, the evidence of this interaction is limited. The objective of this study was to evaluate warfarin dose and international… read more here.
Keywords: initiation; receiving chronic; warfarin; patients receiving ... See more keywords
TCTAP A-084 Multiple Genotypes Affect Warfarin Dose in Korean Patients.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.03.149
Abstract: Asian patients required lower warfarin dose requirements than Caucasians owing to the differences of genetic frequencies. The influences of multiple genotypes on warfarin dosage were not frequently tested in Korean patients. We sought to confirm… read more here.
Keywords: 084 multiple; multiple genotypes; korean patients; tctap 084 ... See more keywords
Performance Evaluation of Warfarin Dose Prediction Algorithms and Effects of Clinical Factors on Warfarin Dose in Chinese Patients.
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DOI: 10.1097/ftd.0000000000000880
Abstract: BACKGROUND The clinical utility of warfarin dose prediction algorithms remains controversial, our purpose is to evaluate the performance of warfarin dose prediction algorithms and the effects of clinical factors on warfarin dose in Chinese patients.… read more here.
Keywords: dose prediction; warfarin dose; prediction algorithms; warfarin ... See more keywords
Integrated analysis of genetic variation and gene expression reveals novel variant for increased warfarin dose requirement in African Americans
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DOI: 10.1111/jth.13639
Abstract: Essentials Genetic variants controlling gene regulation have not been explored in pharmacogenomics. We tested liver expression quantitative trait loci for association with warfarin dose response. A novel predictor for increased warfarin dose response in African… read more here.
Keywords: variation gene; increased warfarin; african americans; expression ... See more keywords
Association between polymorphisms in microRNA seed region and warfarin stable dose
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DOI: 10.1136/postgradmedj-2019-137197
Abstract: Background The optimal dose of anticoagulant warfarin varies among patients to achieve the target international normalised ratio. Although genetic variations related to warfarin pharmacokinetics and vitamin K cycle are important factors associated with warfarin dose… read more here.
Keywords: warfarin; seed; warfarin dose; seed region ... See more keywords
Frequency of Common VKORC1 Polymorphisms and Their Impact on Warfarin Dose Requirement in Pakistani Population
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DOI: 10.1177/1076029616680478
Abstract: Polymorphisms in vitamin K epoxide reductase complex subunit 1 (VKORC1) gene lead to interindividual variability in warfarin dose requirement. The characterization of genotype frequency distribution is required in different populations for construction of customized dosing… read more here.
Keywords: vkorc1 polymorphisms; dose requirement; frequency; warfarin ... See more keywords