CW EPR parameters reveal cytochrome P450 ligand binding modes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2018.02.021
Abstract: Cytochrome P450 (CYP) monoxygenses utilize heme cofactors to catalyze oxidation reactions. They play a critical role in metabolism of many classes of drugs, are an attractive target for drug development, and mediate several prominent drug… read more here.
Keywords: water; binding modes; cytochrome p450; bridged complexes ... See more keywords
The crystal structure of 5-(trifluoromethyl)picolinic acid monohydrate reveals a water-bridged hydrogen-bonding network
Sign Up to like & getrecommendations! Published in 2020 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989020013523
Abstract: The title compound, [systematic name: 5-(trifluoromethyl)pyridine-2-carboxylic acid monohydrate], C7H4F3NO2·H2O, is the acid hydrate of a pyridine with a carboxylic acid group and a trifluoromethyl substituent situated para to one another on the aromatic ring. The… read more here.
Keywords: hydrogen; acid monohydrate; water bridged; acid ... See more keywords