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Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.14220
Abstract: Key Points Question Is myelin damage in normal-appearing white matter associated with cognitive impairment in participants with multiple sclerosis (MS)? Findings In this cross-sectional study of 73 participants with MS and 22 age-, sex-, and… read more here.
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Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28185
Abstract: Myelin water imaging (MWI) using MRI has been introduced as a method to quantify the integrity of myelin in vivo. However, the investigation of its potential to probe myelin changes has been limited. read more here.
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Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15788
Abstract: PURPOSE To enable acceleration in 3D multi-echo gradient echo (mGRE) acquisition for myelin water imaging (MWI) by combining joint parallel imaging (JPI) and joint deep learning (JDL). METHODS We implemented a multi-step reconstruction process using… read more here.
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Published in 2017 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.26551
Abstract: Myelin water imaging (MWI) using multi‐echo T2 relaxation is a quantitative MRI technique that can be used as an in vivo biomarker for myelin in the central nervous system. MWI using a multi‐echo spin echo… read more here.
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Published in 2018 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.27211
Abstract: To compare the recently introduced inhomogeneous magnetization transfer (ihMT) technique with more established MRI techniques including myelin water imaging (MWI) and diffusion tensor imaging (DTI), and to evaluate the microstructural attributes correlating with this new… read more here.
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Published in 2020 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.28199
Abstract: Myelin water imaging (MWI) provides a valuable biomarker for myelin, but clinical application has been restricted by long acquisition times. Accelerating the standard multi‐echo T2 acquisition with gradient echoes (GRASE) or by 2D multi‐slice data… read more here.
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Published in 2021 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.28700
Abstract: To determine whether deuterated water (HDO) generated from the metabolism of [2H7]glucose is a sensitive biomarker of cerebral glycolysis and oxidative flux. read more here.
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Published in 2021 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29125
Abstract: Multicomponent analysis of MRI T2 relaxation time (mcT2) is commonly used for estimating myelin content by separating the signal at each voxel into its underlying distribution of T2 values. This voxel‐based approach is challenging due… read more here.
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Published in 2017 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2017.06.005
Abstract: Quantitative myelin water imaging (MWI) from signal T2* decay acquired with multiple Gradient-Recalled Echo (mGRE) sequence has been widely used since its first report. A recent study showed that with low resolution data (2mm isotropic… read more here.
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Published in 2022 at "Journal of Neuroimaging"
DOI: 10.1111/jon.13064
Abstract: Myelin water fraction (MWF) deficits as measured by myelin water imaging (MWI) have been related to worse motor function in persons with multiple sclerosis (PwMS). However, it is unknown if measures from MWI metrics in… read more here.
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Published in 2018 at "Journal of Applied Remote Sensing"
DOI: 10.1117/1.jrs.12.044001
Abstract: Abstract. The Snow and Water Imaging Spectrometer (SWIS) is a science-grade imaging spectrometer designed for CubeSat integration, spanning a 350- to 1700-nm spectral range with 5.7-nm sampling, a 10-degree field-of-view, and 0.3-mrad spatial resolution. The… read more here.