In colorectal cancer; NMR-monitored β-Catenin inhibition by a Quinoline derivative using Water-LOGSY technique
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DOI: 10.1016/j.molstruc.2021.131151
Abstract: Abstract 2-Amino-4-(2-chloroquinolin-3-yl)-7-hydroxy-4H-chromene-3-carbonitrile (3a) is a quinoline derivative that has been shown to possess antitumor activity. Beside activity, the compound has reasonable solubility in aqueous buffers. Herein, we tested its activity as potential ligand for s-Catenin… read more here.
Keywords: quinoline derivative; colorectal cancer; water logsy;