Oxidative modifications of extracellular matrix promote the second wave of inflammation via β2 integrins.
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DOI: 10.1182/blood-2017-10-810176
Abstract: Early stages of inflammation are characterized by extensive oxidative insult by recruited and activated neutrophils. Secretion of peroxidases, including the main enzyme, myeloperoxidase, leads to the generation of reactive oxygen species. We show that this… read more here.
Keywords: cep; wave inflammation; extracellular matrix; oxidative modifications ... See more keywords