Assessment of Risk of Xerostomia After Whole-Brain Radiation Therapy and Association With Parotid Dose
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2018.4951
Abstract: Importance Whole-brain radiation therapy (WBRT) delivers a substantial radiation dose to the parotid glands, but the parotid glands are not delineated for avoidance and xerostomia has never been reported as an adverse effect. Minimizing the… read more here.
Keywords: parotid dose; xerostomia; parotid; wbrt ... See more keywords
Role of radiation therapy in primary central nervous system lymphoma
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DOI: 10.1007/s11060-017-2616-4
Abstract: We analyzed patterns of care and outcomes for patients with primary central nervous system lymphoma (PCNSL) in this multi-institutional retrospective study. Between January 2000 and December 2011, 220 patients with PCNSL received radiotherapy (RT). Among… read more here.
Keywords: system lymphoma; nervous system; central nervous; primary central ... See more keywords
Whole brain radiotherapy for non-small cell lung cancer
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DOI: 10.1016/s0140-6736(17)30895-4
Abstract: 1394 www.thelancet.com Vol 389 April 8, 2017 brain radiotherapy (WBRT) versus optimal supportive care in patients with non-small cell lung cancer (NSCLC) and brain metastases. We commend the authors on undertaking this important study. This… read more here.
Keywords: brain radiotherapy; radiotherapy; non small; wbrt ... See more keywords
WHOLE BRAIN RADIOTHERAPY FOR INTRACRANIAL METASTATIC DISEASE IN NON-SMALL CELL LUNG CANCER: THE WESSEX EXPERIENCE
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DOI: 10.1093/neuonc/noae158.051
Abstract: The QUARTZ trial (2016) reported that corticosteroid therapy was non-inferior to whole brain radiotherapy(WBRT) for non-small cell lung cancer (NSCLC) with regards overall survival(OS). This is a single centre experience of WBRT for NSCLC in… read more here.
Keywords: disease; therapy; whole brain; radiotherapy ... See more keywords
NCOG-20. Stereotactic radiation versus hippocampal avoidant whole brain radiation in patients with 5-20 brain metastases: Cognitive outcomes of 12-month survivors
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DOI: 10.1093/neuonc/noaf201.1287
Abstract: Compared to whole brain radiation (WBRT), stereotactic radiation (SRS/SRT) and Hippocampal Avoidant (HA)-WBRT produce superior neurocognitive function (NCF) outcomes for brain metastasis survivors. In a multi-center, phase 3 randomized clinical trial comparing SRS/SRT to HA-WBRT… read more here.
Keywords: month; brain; brain metastases; radiation ... See more keywords
RTHP-26. DOSIMETRIC FEASIBILITY STUDY USING HIPPOCAMPAL AVOIDANCE WITH SIMULTANEOUS INTEGRATED BOOST WHOLE BRAIN RADIOTHERAPY (HA-SIB-WBRT)
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DOI: 10.1093/neuonc/noz175.897
Abstract: Recently Hippocampal Avoidance (HA-) WBRT has become a recommended treatment option in patients with multiple (≥ 5) brain metastases and good prognosis. We wanted to investigate the dosimetric feasibility of dose painting technique combining HA-WBRT… read more here.
Keywords: simultaneous integrated; wbrt; brain; integrated boost ... See more keywords
Radiation Optic Neuropathy After Whole-Brain Radiation Therapy.
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DOI: 10.1097/wno.0000000000000765
Abstract: R adiation optic neuropathy (RON) is a rare complication of external beam radiation therapy (RT) in which exposure of the anterior visual pathway (AVP) to radiation results in acute, painless vision loss in one or… read more here.
Keywords: wbrt; radiation therapy; radiation; optic neuropathy ... See more keywords
Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol
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DOI: 10.1186/s12885-020-07565-y
Abstract: Background Recent evidence supports hippocampal avoidance with whole brain radiotherapy (HA-WBRT) as the recommended treatment option in patients with good prognosis and multiple brain metastases as this results in better neurocognitive preservation compared to whole… read more here.
Keywords: brain metastases; sib; control; radiotherapy ... See more keywords
Single center long term results from the randomized phase-3 TARGIT-A trial comparing intraoperative (IORT) and whole-breast radiation therapy (WBRT) for early breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e12616
Abstract: e12616Background: Partial breast irradiation using IORT after breast conserving surgery is non-inferior to WBRT for a selected group of breast cancer patients. We report the results of patients treated in our center as a part… read more here.
Keywords: targit trial; breast; breast cancer; wbrt ... See more keywords
NRG Oncology CC001: A phase III trial of hippocampal avoidance (HA) in addition to whole-brain radiotherapy (WBRT) plus memantine to preserve neurocognitive function (NCF) in patients with brain metastases (BM).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.2009
Abstract: 2009 Background: NRG CC001, a phase III trial of WBRT plus memantine (WBRT+M) with or without HA, sought to evaluate the neuro-protective effects of lowering the hippocampal radiation dose. Methods: Patients (pts) with BM were… read more here.
Keywords: wbrt; oncology; ncf failure; trial ... See more keywords
Induction bevacizumab, etoposide and cisplatin followed by whole brain radiotherapy (WBRT) versus WBRT alone in breast cancer with untreated brain metastases: Results of a randomized phase II A-PLUS trial.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.1082
Abstract: 1082Background: Our previous study (Clin Cancer Res. 2015;21(8):1851) demonstrated that bevacizumab preconditioning followed by etoposide and cisplatin (BEEP) is a highly effective treatment for br... read more here.
Keywords: bevacizumab; etoposide cisplatin; cancer; wbrt ... See more keywords