Assessment of Risk of Xerostomia After Whole-Brain Radiation Therapy and Association With Parotid Dose
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2018.4951
Abstract: Importance Whole-brain radiation therapy (WBRT) delivers a substantial radiation dose to the parotid glands, but the parotid glands are not delineated for avoidance and xerostomia has never been reported as an adverse effect. Minimizing the… read more here.
Keywords: parotid dose; xerostomia; parotid; wbrt ... See more keywords
Role of radiation therapy in primary central nervous system lymphoma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-017-2616-4
Abstract: We analyzed patterns of care and outcomes for patients with primary central nervous system lymphoma (PCNSL) in this multi-institutional retrospective study. Between January 2000 and December 2011, 220 patients with PCNSL received radiotherapy (RT). Among… read more here.
Keywords: system lymphoma; nervous system; central nervous; primary central ... See more keywords
Whole brain radiotherapy for non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "The Lancet"
DOI: 10.1016/s0140-6736(17)30895-4
Abstract: 1394 www.thelancet.com Vol 389 April 8, 2017 brain radiotherapy (WBRT) versus optimal supportive care in patients with non-small cell lung cancer (NSCLC) and brain metastases. We commend the authors on undertaking this important study. This… read more here.
Keywords: brain radiotherapy; radiotherapy; non small; wbrt ... See more keywords
RTHP-26. DOSIMETRIC FEASIBILITY STUDY USING HIPPOCAMPAL AVOIDANCE WITH SIMULTANEOUS INTEGRATED BOOST WHOLE BRAIN RADIOTHERAPY (HA-SIB-WBRT)
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.897
Abstract: Recently Hippocampal Avoidance (HA-) WBRT has become a recommended treatment option in patients with multiple (≥ 5) brain metastases and good prognosis. We wanted to investigate the dosimetric feasibility of dose painting technique combining HA-WBRT… read more here.
Keywords: simultaneous integrated; wbrt; brain; integrated boost ... See more keywords
Radiation Optic Neuropathy After Whole-Brain Radiation Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Ophthalmology"
DOI: 10.1097/wno.0000000000000765
Abstract: R adiation optic neuropathy (RON) is a rare complication of external beam radiation therapy (RT) in which exposure of the anterior visual pathway (AVP) to radiation results in acute, painless vision loss in one or… read more here.
Keywords: wbrt; radiation therapy; radiation; optic neuropathy ... See more keywords
Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol
Sign Up to like & getrecommendations! Published in 2020 at "BMC Cancer"
DOI: 10.1186/s12885-020-07565-y
Abstract: Background Recent evidence supports hippocampal avoidance with whole brain radiotherapy (HA-WBRT) as the recommended treatment option in patients with good prognosis and multiple brain metastases as this results in better neurocognitive preservation compared to whole… read more here.
Keywords: brain metastases; sib; control; radiotherapy ... See more keywords
Single center long term results from the randomized phase-3 TARGIT-A trial comparing intraoperative (IORT) and whole-breast radiation therapy (WBRT) for early breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e12616
Abstract: e12616Background: Partial breast irradiation using IORT after breast conserving surgery is non-inferior to WBRT for a selected group of breast cancer patients. We report the results of patients treated in our center as a part… read more here.
Keywords: targit trial; breast; breast cancer; wbrt ... See more keywords
NRG Oncology CC001: A phase III trial of hippocampal avoidance (HA) in addition to whole-brain radiotherapy (WBRT) plus memantine to preserve neurocognitive function (NCF) in patients with brain metastases (BM).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.2009
Abstract: 2009 Background: NRG CC001, a phase III trial of WBRT plus memantine (WBRT+M) with or without HA, sought to evaluate the neuro-protective effects of lowering the hippocampal radiation dose. Methods: Patients (pts) with BM were… read more here.
Keywords: wbrt; oncology; ncf failure; trial ... See more keywords
Induction bevacizumab, etoposide and cisplatin followed by whole brain radiotherapy (WBRT) versus WBRT alone in breast cancer with untreated brain metastases: Results of a randomized phase II A-PLUS trial.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.1082
Abstract: 1082Background: Our previous study (Clin Cancer Res. 2015;21(8):1851) demonstrated that bevacizumab preconditioning followed by etoposide and cisplatin (BEEP) is a highly effective treatment for br... read more here.
Keywords: bevacizumab; etoposide cisplatin; cancer; wbrt ... See more keywords
Survival and prognostic factors in patients undergoing the resection of solitary brain metastasis from non-small cell lung cancer: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thoracic Disease"
DOI: 10.21037/jtd-22-1279
Abstract: Background Neurosurgery is the standard of care for resectable solitary brain metastasis (BM) from non-small cell lung cancer (NSCLC), but still with a poor outcome. Postoperative whole-brain radiotherapy (WBRT) was reported to reduce local recurrence,… read more here.
Keywords: cell; prognostic factors; brain; wbrt ... See more keywords
WBRT for brain metastases from non-small cell lung cancer: for whom and when?—Contemporary point of view
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thoracic Disease"
DOI: 10.21037/tcr-2019-rbmlc-06
Abstract: The incidence of brain metastases (BM) is estimated between 20% and 40% of patients with solid cancer. The most common cause of this failure is lung cancer, and in locally advanced non-small cell lung cancer… read more here.
Keywords: wbrt; treatment; lung cancer; cancer ... See more keywords