In vivo efficacy of WCK 6777 (ertapenem/zidebactam) against carbapenemase-producing Klebsiella pneumoniae in the neutropenic murine pneumonia model
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DOI: 10.1093/jac/dkac110
Abstract: Abstract Objectives Ertapenem has proven to be an effective antimicrobial; however, increasing enzyme-mediated resistance has been noted. Combination with zidebactam, a β-lactam enhancer, is restorative. Human-simulated regimens (HSRs) of ertapenem and zidebactam alone and in… read more here.
Keywords: zidebactam; ertapenem zidebactam; efficacy; wck 6777 ... See more keywords