Wdr5-mediated H3K4 methylation facilitates HSPC development via maintenance of genomic stability in zebrafish
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DOI: 10.1073/pnas.2420534122
Abstract: Significance Hematopoietic stem and progenitor cells (HSPCs) undergo rapid proliferation during embryonic development, establishing the foundation for lifelong hematopoiesis. Genomic stability is crucial for HSPC proliferation; however, the precise regulation of genomic stability to ensure… read more here.
Keywords: mediated h3k4; stability; wdr5 mediated; h3k4 methylation ... See more keywords