Endothelin-1 regulation is entangled in a complex web of epigenetic mechanisms in diabetes.
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DOI: 10.33549/physiolres.933836
Abstract: Endothelial cells (ECs) are primary targets of glucose-induced tissue damage. As a result of hyperglycemia, endothelin-1 (ET-1) is upregulated in organs affected by chronic diabetic complications. The objective of the present study was to identify… read more here.
Keywords: complex web; methylation; web epigenetic; epigenetic mechanisms ... See more keywords