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Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2829
Abstract: Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin lymphoma (NHL) and is a clinical, pathological, and molecular heterogeneous disease with highly variable clinical outcomes. Currently, valid prognostic biomarkers in DLBCL are…
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Keywords:
lymphoma;
gene expression;
web server;
gene ... See more keywords
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Published in 2017 at "Human Mutation"
DOI: 10.1002/humu.23125
Abstract: Exome sequencing has been widely used to identify the genetic variants underlying human genetic disorders for clinical diagnoses, but the identification of pathogenic sequence variants among the huge amounts of benign ones is complicated and…
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Keywords:
exome sequencing;
pathogenic sequence;
web server;
sequence variants ... See more keywords
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Published in 2018 at "Biochimie"
DOI: 10.1016/j.biochi.2018.06.002
Abstract: Though RNA G-quadruplexes became a focus of study over a decade ago, the main challenge associated with the identification of new potential G-quadruplexes remains a bottleneck step. It slows the study of these non-canonical structures…
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Keywords:
screener web;
g4rna screener;
screener;
web server ... See more keywords
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Published in 2019 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2018.12.015
Abstract: Evolution builds up new genetic material from existing ones, not in random, but in highly ordered and eloquent patterns. Most of these sequence repeats are revelatory of valuable information contributing to areas of disease research…
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Keywords:
server extract;
web server;
repex web;
sequence repeats ... See more keywords
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Published in 2018 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.07.021
Abstract: The current software/algorithms for high-throughput sequence data analysis are not user-friendly. We developed MATHT, the Multifaceted Analysis Tool for Human Transcriptome, which is a free web server available at www.biocloudservice.com, to provide more comprehensive and…
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Keywords:
matht web;
data analysis;
analysis;
web server ... See more keywords
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Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c04555
Abstract: Angiotensin converting enzyme-I (ACE-I) is a key therapeutic target of the renin-angiotensin-aldosterone system (RAAS), the central pathway of blood pressure regulation. Food-derived peptides with ACE-I inhibitory activities are receiving significant research attention. However, identification of…
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Keywords:
web server;
ace inhibitory;
food;
angiotensin converting ... See more keywords
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Published in 2020 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.0c00779
Abstract: We present a novel web server, named gridSolvate, dedicated to the prediction of biomolecular hydration properties. Given a solute in atomic representation, such as a protein or protein–ligand complex, the server determines positions and excess…
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Keywords:
prediction biomolecular;
biomolecular hydration;
web server;
hydration properties ... See more keywords
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Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00964
Abstract: Cells express thousands of macromolecules, and their functioning relies on multiple networks of intermolecular interactions. These interactions can be experimentally determined at different spatial and temporal resolutions. But, physical interfaces are not often delineated directly,…
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Keywords:
web server;
linear motif;
short linear;
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Published in 2025 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.4c00700
Abstract: Hydrogen–deuterium exchange monitored by mass spectrometry (HDX–MS) is a well-established and powerful technique used to study protein dynamics and stability by capturing local and global unfolding events in protein structures. However, in this technique, obtaining…
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Keywords:
deuterium uptake;
hdx data;
hradex;
high resolution ... See more keywords
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Published in 2024 at "Chinese Physics B"
DOI: 10.1088/1674-1056/ad47e5
Abstract: FL-Online (http://fanlab.ac.cn) is an out-of-box modern web service featuring a user-friendly interface and simplified parameters, providing academic users with access to a series of online programs for biomolecular crystallography, including SAPI-online, OASIS-online, C-IPCAS-online and a…
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Keywords:
web server;
ray crystallographic;
online;
web ... See more keywords
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Published in 2025 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbaf424
Abstract: Abstract Allosteric regulation is essential for modulating protein function and represents a promising target for therapeutic intervention, yet the complex dynamics of the protein nanoenvironment hinder the reliable identification of allosteric sites. Traditional pocket-based predictors…
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Keywords:
protein nanoenvironment;
protein;
usepackage;
allosteric site ... See more keywords