RAP: A Web Tool for RNA-Seq Data Analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1307-8_21
Abstract: Since 1950 main studies of RNA regarded its role in the protein synthesis. Later insights showed that only a small portion of RNA codes for proteins where the rest could have different functional roles. With… read more here.
Keywords: web tool; analysis; rna seq; seq data ... See more keywords
Development of a spatial web tool to identify hotspots of environmental burdens in Wallonia (Belgium)
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-04418-5
Abstract: In response to the Walloon Environment and Health Program, the Scientific Institute of Public Services (ISSeP) developed an integrated approach of environmental exposure assessment in the Walloon region, Belgium. The study presents an index-based approach… read more here.
Keywords: web tool; tool; environmental burdens; health ... See more keywords
PyFragMS—A Web Tool for the Investigation of the Collision-Induced Fragmentation Pathways
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c07272
Abstract: Dissociation induced by the accumulation of internal energy via collisions of ions with neutral molecules is one of the most important fragmentation techniques in mass spectrometry (MS), and the identification of small singly charged molecules… read more here.
Keywords: tool investigation; fragmentation; isotopically labeled; web tool ... See more keywords
Digenome-seq web tool for profiling CRISPR specificity
Sign Up to like & getrecommendations! Published in 2017 at "Nature Methods"
DOI: 10.1038/nmeth.4262
Abstract: To the Editor: We recently reported Digenome-seq (digested genome sequencing), a method for in vitro identification of potential off-target sites, and we evaluated the specificity of CRISPR– Cas9 (refs. 1,2) and CRISPR–Cpf1(ref. 3) endonuclease by… read more here.
Keywords: web tool; digenome seq; tool; specificity ... See more keywords
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42717
Abstract: To be effective as a drug, a potent molecule must reach its target in the body in sufficient concentration, and stay there in a bioactive form long enough for the expected biologic events to occur.… read more here.
Keywords: web tool; chemistry; pharmacokinetics drug; drug ... See more keywords
MDCKpred: a web-tool to calculate MDCK permeability coefficient of small molecule using membrane-interaction chemical features
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2018.1499840
Abstract: Abstract Structure-based models to understand the transport of small molecules through biological membrane can be developed by enumerating intermolecular interactions of the small molecule with a biological membrane, usually a dimyristoylphosphatidylcholine (DMPC) monolayer. This ADME… read more here.
Keywords: web tool; mdck permeability; small molecule; mdckpred web ... See more keywords
TRI_tool: a web-tool for prediction of protein–protein interactions in human transcriptional regulation
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btw590
Abstract: Summary: The TRI_tool, a sequence-based web tool for prediction of protein interactions in the human transcriptional regulation, is intended for biomedical investigators who work on understanding the regulation of gene expression. It has an improved… read more here.
Keywords: protein; web tool; tool prediction; tri tool ... See more keywords
CNVxplorer: a web tool to assist clinical interpretation of CNVs in rare disease patients
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab347
Abstract: Abstract Copy Number Variants (CNVs) are an important cause of rare diseases. Array-based Comparative Genomic Hybridization tests yield a ∼12% diagnostic rate, with ∼8% of patients presenting CNVs of unknown significance. CNVs interpretation is particularly… read more here.
Keywords: web tool; interpretation; cnvxplorer web; disease ... See more keywords
LoopGrafter: a web tool for transplanting dynamical loops for protein engineering
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac249
Abstract: Abstract The transplantation of loops between structurally related proteins is a compelling method to improve the activity, specificity and stability of enzymes. However, despite the interest of loop regions in protein engineering, the available methods… read more here.
Keywords: loopgrafter web; web tool; loopgrafter; protein engineering ... See more keywords
Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad390
Abstract: Functional precision medicine (fPM) offers an exciting, simplified approach to finding the right applications for existing molecules and enhancing therapeutic potential. Integrative and robust tools ensuring high accuracy and reliability of the results are critical.… read more here.
Keywords: breeze; analysis; drug response; drug ... See more keywords
WEGO 2.0: a web tool for analyzing and plotting GO annotations, 2018 update
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky400
Abstract: Abstract WEGO (Web Gene Ontology Annotation Plot), created in 2006, is a simple but useful tool for visualizing, comparing and plotting GO (Gene Ontology) annotation results. Owing largely to the rapid development of high-throughput sequencing… read more here.
Keywords: web tool; ontology; wego; tool analyzing ... See more keywords