Novel methods for the analysis of stepped wedge cluster randomized trials.
Sign Up to like & getrecommendations! Published in 2019 at "Statistics in medicine"
DOI: 10.1002/sim.8451
Abstract: Stepped wedge cluster randomized trials (SW-CRTs) have become increasingly popular and are used for a variety of interventions and outcomes, often chosen for their feasibility advantages. SW-CRTs must account for time trends in the outcome… read more here.
Keywords: analysis; cluster randomized; stepped wedge; wedge cluster ... See more keywords
Variations in stepped-wedge cluster randomized trial design: Insights from the Patient-Centered Care Transitions in Heart Failure trial.
Sign Up to like & getrecommendations! Published in 2019 at "American heart journal"
DOI: 10.1016/j.ahj.2019.08.017
Abstract: The stepped-wedge (SW) cluster randomized controlled trial, in which clusters cross over in a randomized sequence from control to intervention, is ideal for the implementation and testing of complex health service interventions. In certain cases… read more here.
Keywords: trial; heart; stepped wedge; wedge cluster ... See more keywords
Sample size calculators for planning stepped-wedge cluster randomized trials: a review and comparison.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of epidemiology"
DOI: 10.1093/ije/dyac123
Abstract: Recent years have seen a surge of interest in stepped-wedge cluster randomized trials (SW-CRTs). SW-CRTs include several design variations and methodology is rapidly developing. Accordingly, a variety of power and sample size calculation software for… read more here.
Keywords: sample size; stepped wedge; wedge cluster; size ... See more keywords
011 High-sensitivity cardiac troponin on presentation to rule out myocardial infarction (HiSTORIC): a stepped-wedge cluster randomised controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "Emergency Medicine Journal"
DOI: 10.1136/emermed-2019-rcem.11
Abstract: Background High-sensitivity troponin (hs-cTn) assays enable MI to be ruled out earlier, but the effectiveness and safety of this approach is uncertain. We compared a conventional pathway using the 99th centile and serial testing at… read more here.
Keywords: wedge cluster; presentation; rule; high sensitivity ... See more keywords
Sample size determination for stepped wedge cluster randomized trials in pragmatic settings
Sign Up to like & getrecommendations! Published in 2021 at "Statistical Methods in Medical Research"
DOI: 10.1177/09622802211022392
Abstract: The stepped-wedge cluster randomized design has been increasingly employed by pragmatic trials in health services research. In this study, based on the GEE approach, we present closed-form sample size calculation that is applicable to both… read more here.
Keywords: sample size; stepped wedge; wedge cluster; cluster randomized ... See more keywords
Crowdsourcing to expand HIV testing among men who have sex with men in China: A closed cohort stepped wedge cluster randomized controlled trial
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Medicine"
DOI: 10.1371/journal.pmed.1002645
Abstract: Background HIV testing rates are suboptimal among at-risk men. Crowdsourcing may be a useful tool for designing innovative, community-based HIV testing strategies to increase HIV testing. The purpose of this study was to use a… read more here.
Keywords: intervention; hiv; hiv testing; among men ... See more keywords
Mixed effects approach to the analysis of the stepped wedge cluster randomised trial—Investigating the confounding effect of time through simulation
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DOI: 10.1371/journal.pone.0208876
Abstract: Background A stepped wedge cluster randomised trial (SWCRT) is a multicentred study which allows an intervention to be rolled out at sites in a random order. Once the intervention is initiated at a site, all… read more here.
Keywords: intervention; cluster randomised; time; mixed effects ... See more keywords
Remote Stewardship for Medically Underserved Nurseries: A Stepped-Wedge, Cluster Randomized Study.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatrics"
DOI: 10.1542/peds.2021-055686
Abstract: BACKGROUND AND OBJECTIVES Antibiotic overuse is associated with adverse neonatal outcomes. Many medically underserved centers lack pediatric antibiotic stewardship program (ASP) support. Telestewardship may mitigate this disparity. Authors of this study aimed to determine the… read more here.
Keywords: stewardship; stepped wedge; wedge cluster; medically underserved ... See more keywords