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Power analysis for stepped wedge trials with multiple interventions

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2 Published in 2022 at "Statistics in Medicine"

DOI: 10.1002/sim.9301

Abstract: Stepped wedge design (SWD) trials are cluster randomized trials that feature staggered, unidirectional cross‐over between treatment conditions. Existing literature on power for SWDs focuses primarily on designs with two conditions, typically a control and an… read more here.

Keywords: wedge trials; analysis stepped; power; stepped wedge ... See more keywords

Model misspecification in stepped wedge trials: Random effects for time or treatment

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1 Published in 2022 at "Statistics in Medicine"

DOI: 10.1002/sim.9326

Abstract: Mixed models are commonly used to analyze stepped wedge trials (SWTs) to account for clustering and repeated measures on clusters. One critical issue researchers face is whether to include a random time effect or a… read more here.

Keywords: wedge trials; stepped wedge; effect; treatment ... See more keywords

Key concepts in clinical epidemiology: Stepped wedge trials.

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0 Published in 2021 at "Journal of clinical epidemiology"

DOI: 10.1016/j.jclinepi.2021.04.003

Abstract: A stepped wedge trial evaluates an intervention that is implemented over a number of time periods according to a staggered timetable. Stepped wedge trials are usually cluster randomised, the intervention being delivered at some geographical,… read more here.

Keywords: intervention; wedge trials; clinical epidemiology; epidemiology ... See more keywords