Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2018.12.001
Abstract: Objective Structurally-improved GIP analogs were developed to determine precisely whether GIP receptor (GIPR) agonism or antagonism lowers body weight in obese mice. Methods A series of peptide-based GIP analogs, including structurally diverse agonists and a… read more here.
Keywords: weight lowering; gipr; mice; body weight ... See more keywords
In adults with overweight or obesity, adding weight-lowering drugs to lifestyle modification improves weight loss
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Internal Medicine"
DOI: 10.7326/j22-0024
Abstract: SOURCE CITATION Shi Q, Wang Y, Hao Q, et al. Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials. Lancet. 2022;399:259-69. 34895470. read more here.
Keywords: overweight obesity; weight lowering; obesity adding; adding weight ... See more keywords