Global transcriptome and weighted gene co-expression network analyses reveal hybrid-specific modules and candidate genes related to plant height development in maize
Sign Up to like & getrecommendations! Published in 2018 at "Plant Molecular Biology"
DOI: 10.1007/s11103-018-0763-4
Abstract: AbstractKey message Weighted gene co-expression network analysis was explored to find key hub genes involved in plant height regulation.AbstractPlant height, an important trait for maize breeding because of its close relatedness to lodging resistance and… read more here.
Keywords: weighted gene; network; plant; plant height ... See more keywords
Application of Weighted Gene Co-expression Network Analysis for Data from Paired Design
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18705-z
Abstract: Investigating how genes jointly affect complex human diseases is important, yet challenging. The network approach (e.g., weighted gene co-expression network analysis (WGCNA)) is a powerful tool. However, genomic data usually contain substantial batch effects, which… read more here.
Keywords: weighted gene; network; paired design; gene expression ... See more keywords
Identification of Key Modules and Hub Genes of Keloids with Weighted Gene Coexpression Network Analysis
Sign Up to like & getrecommendations! Published in 2017 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000003014
Abstract: Background: Keloid scarring impairs patients’ quality of life, and although many therapeutic strategies have been developed, most remain unsatisfactory because of limited understanding of the mechanisms underlying keloid development. Methods: A microarray gene expression data… read more here.
Keywords: weighted gene; analysis; hub genes; gene coexpression ... See more keywords
Weighted gene coexpression network analysis reveals hub genes involved in cholangiocarcinoma progression and prognosis
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology Research"
DOI: 10.1111/hepr.13386
Abstract: Cholangiocarcinoma (CCA) is a highly malignant tumor found in the bile duct epithelial cells, and the second most common primary tumor of the liver. However, the pivotal roles of molecular biomarkers in oncogenesis of CCA… read more here.
Keywords: analysis reveals; weighted gene; gene coexpression; progression ... See more keywords
Identification of Key Genes in Severe Burns by Using Weighted Gene Coexpression Network Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/5220403
Abstract: The aims of this work were to explore the use of weighted gene coexpression network analysis (WGCNA) for identifying the key genes in severe burns and to provide a reference for finding therapeutic targets for… read more here.
Keywords: network; weighted gene; gene coexpression; coexpression network ... See more keywords
Identification of Key Genes Related to the Obesity Patients with Osteoarthritis Based on Weighted Gene Coexpression Network Analysis (WGCNA)
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/8953807
Abstract: Background Increasing evidence has suggested that obesity affects the occurrence and progression of osteoarthritis (OA). However, the underlying molecular mechanism that obesity affects the course of OA is not fully understood and remains to be… read more here.
Keywords: hub genes; network; weighted gene; analysis ... See more keywords
Potential Role of the Chemotaxis System in Formation and Progression of Intracranial Aneurysms Through Weighted Gene Co-Expression Network Analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s347420
Abstract: Background Intracranial aneurysm (IA) is the most common and is the main cause of spontaneous subarachnoid hemorrhage (SAH). The underlying molecular mechanisms for preventing IA progression have not been fully identified. Our research aimed to… read more here.
Keywords: weighted gene; expression network; analysis; gene expression ... See more keywords
Weighted Gene Coexpression Network Analysis Identifies Specific Modules and Hub Genes Related to Major Depression
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s244452
Abstract: Purpose Despite advances in characterizing the neurobiology of emotional disorders, there is still a significant lack of scientific understanding of the pathophysiological mechanisms governing major depressive disorder (MDD). This study attempted to elucidate the molecular… read more here.
Keywords: weighted gene; gene coexpression; analysis; gene ... See more keywords
Identification of hub miRNA biomarkers for bladder cancer by weighted gene coexpression network analysis
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DOI: 10.2147/ott.s146479
Abstract: Bladder cancer (BC) is a common urinary system tumor with high aggressiveness, and it results in relatively high mortality due to a lack of precise and suitable biomarkers. In this study, we applied the weighted… read more here.
Keywords: bladder cancer; weighted gene; network; hub ... See more keywords
A novel nomogram associated with regulatory T cells infiltration by weighted gene co-expression network analysis for predicting survival in patients with colon cancer.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202211_30161
Abstract: OBJECTIVE Traditional diagnostic strategies are unable to accurately discriminate between patients with poor and satisfied prognosis in colon cancer. Therefore, it is urgently recommended to identify new biomarkers in favor of better selection of patients… read more here.
Keywords: network analysis; colon cancer; weighted gene; colon ... See more keywords
Construction of a Competitive Endogenous RNA Network for Pancreatic Adenocarcinoma Based on Weighted Gene Co-expression Network Analysis and a Prognosis Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00515
Abstract: Pancreatic adenocarcinoma (PAAD) is a pancreatic disease with considerable mortality worldwide. Because of a lack of obvious symptoms at the early stage, most PAAD patients are diagnosed at the terminal stage and prognosis is usually… read more here.
Keywords: weighted gene; network; analysis; pancreatic adenocarcinoma ... See more keywords