Ligand-Enabled, Palladium-Catalyzed β-C(sp3)-H Arylation of Weinreb Amides.
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DOI: 10.1021/acscatal.8b03014
Abstract: We report the development of Pd(II)-catalyzed C(sp3)-H arylation of Weinreb amides. This work demonstrates the first example of using Weinreb amide as a directing group for transition metal-catalyzed C(sp3)-H activation. Both the inductive effect and… read more here.
Keywords: arylation weinreb; weinreb; catalyzed sp3; weinreb amides ... See more keywords