β-Branched Amino Acids Stabilize Specific Conformations of Cyclic Hexapeptides.
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DOI: 10.1016/j.bpj.2018.12.015
Abstract: Cyclic peptides (CPs) are a promising class of molecules for drug development, particularly as inhibitors of protein-protein interactions. Predicting low-energy structures and global structural ensembles of individual CPs is critical for the design of bioactive… read more here.
Keywords: cyclic hexapeptides; amino acids; well structured; global structural ... See more keywords
Minor hallucinations in Parkinson disease
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DOI: 10.1212/wnl.0000000000007913
Abstract: Objective Psychosis is one of the most debilitating complications of Parkinson disease (PD). Although research on PD psychosis has been focused on the study of well-structured visual hallucinations (VH), currently accepted National Institute of Neurological… read more here.
Keywords: parkinson disease; well structured; hallucinations parkinson; minor hallucinations ... See more keywords