Elevated YKL-40 serum levels may contribute to wet age-related macular degeneration via the ERK1/2 pathway.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS open bio"
DOI: 10.1002/2211-5463.13223
Abstract: Choroidal neovascularization (CNV) is a key characteristic of wet age-related macular degeneration (AMD) that can lead to severe vision loss in the elderly. Anti-VEGF therapy is currently the premier strategy for wet AMD, but it… read more here.
Keywords: age related; erk1 pathway; wet age; wet amd ... See more keywords
What Effect Does Ethnicity Have on the Response to Ranibizumab in the Treatment of Wet Age-Related Macular Degeneration?
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DOI: 10.1159/000486403
Abstract: Aims: To compare, in a single urban population, the visual outcomes of ranibizumab monotherapy in “White” (W) and “Non-White” (NW) patients with wet age-related macular degeneration (AMD). Procedures: Prospective data was collected from 434 eyes… read more here.
Keywords: macular degeneration; age related; related macular; treatment ... See more keywords
Long-term effects of intravitreal bevacizumab and aflibercept on intraocular pressure in wet age-related macular degeneration
Sign Up to like & getrecommendations! Published in 2021 at "BMC Ophthalmology"
DOI: 10.1186/s12886-021-02076-1
Abstract: Background To evaluate the incidence of sustained elevation of intraocular pressure (SE-IOP) associated with intravitreal injections of anti-vascular endothelial growth factors (anti-VEGF) bevacizumab and aflibercept in patients with wet age-related macular degeneration (wAMD). Methods A… read more here.
Keywords: anti vegf; incidence; bevacizumab aflibercept; intraocular pressure ... See more keywords
Short-Term Effects of Brolucizumab in the Treatment of Wet Age-Related Macular Degeneration or Polypoidal Choroidopathy Refractory to Previous Anti-Vascular Endothelial Growth Factor Therapy
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DOI: 10.3390/medicina58121703
Abstract: Background and objectives: To report the initial response to a single intravitreal brolucizumab (IVI-B) injection in wet age-related macular degeneration (wAMD) or polypoidal choroidopathy (PCV) complicated with either persistent subretinal fluid (SRF) or pigment epithelial… read more here.
Keywords: wet age; related macular; age related; first ivi ... See more keywords
Preclinical Evaluation of UDCA-Containing Oral Formulation in Mice for the Treatment of Wet Age-Related Macular Degeneration
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DOI: 10.3390/pharmaceutics11110561
Abstract: As a posterior ocular disease, wet age-related macular degeneration (WAMD) has been known to be related to vision loss, accompanying ocular complications. The intravitreous injection of VEGF antibodies has been reported to be an effective… read more here.
Keywords: age related; related macular; treatment; wet age ... See more keywords