Elevated YKL-40 serum levels may contribute to wet age-related macular degeneration via the ERK1/2 pathway.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS open bio"
DOI: 10.1002/2211-5463.13223
Abstract: Choroidal neovascularization (CNV) is a key characteristic of wet age-related macular degeneration (AMD) that can lead to severe vision loss in the elderly. Anti-VEGF therapy is currently the premier strategy for wet AMD, but it… read more here.
Keywords: age related; erk1 pathway; wet age; wet amd ... See more keywords
Comparative Study on Anti-VEGF in Wet Age-Related Macular Degeneration in the Setting Based on Lean Methodology from the Bari Intravitreal Injection Registry (BIVIR)
Sign Up to like & getrecommendations! Published in 2024 at "Ophthalmology and Therapy"
DOI: 10.1007/s40123-024-00927-w
Abstract: Optimizing treatment protocols for wet age-related macular degeneration (wAMD) is an ongoing challenge, as it involves a delicate balance between achieving therapeutic efficacy and minimizing invasive procedures' frequency. This study aimed to apply the Lean… read more here.
Keywords: methodology; wet age; comparative study; lean methodology ... See more keywords
Olink Profiling of Aqueous Humor Identifies Novel Biomarkers for Wet Age-Related Macular Degeneration.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.4c00195
Abstract: Metabolic dysfunction is recognized as a contributing factor in the pathogenesis of wet age-related macular degeneration (wAMD). However, the specific metabolism-related proteins implicated in wAMD remain elusive. In this study, we assessed the expression profiles… read more here.
Keywords: related macular; wet age; age related; angptl7 metrnl ... See more keywords
What Effect Does Ethnicity Have on the Response to Ranibizumab in the Treatment of Wet Age-Related Macular Degeneration?
Sign Up to like & getrecommendations! Published in 2018 at "Ophthalmologica"
DOI: 10.1159/000486403
Abstract: Aims: To compare, in a single urban population, the visual outcomes of ranibizumab monotherapy in “White” (W) and “Non-White” (NW) patients with wet age-related macular degeneration (AMD). Procedures: Prospective data was collected from 434 eyes… read more here.
Keywords: macular degeneration; age related; related macular; treatment ... See more keywords
Causal effect analysis of the relationship between Alzheimer's diseas (AD) and wet age-related macular degeneration (wAMD)
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Ophthalmology"
DOI: 10.1177/11206721251322219
Abstract: Purpose Alzheimer's disease (AD) and wet age-related macular degeneration (wAMD) are both prevalent degenerative diseases in the elderly population. However, whether AD is causally related to wAMD is unclear. A Mendelian randomization(MR) analysis was conducted… read more here.
Keywords: related macular; wet age; wamd; analysis ... See more keywords
Long-term effects of intravitreal bevacizumab and aflibercept on intraocular pressure in wet age-related macular degeneration
Sign Up to like & getrecommendations! Published in 2021 at "BMC Ophthalmology"
DOI: 10.1186/s12886-021-02076-1
Abstract: Background To evaluate the incidence of sustained elevation of intraocular pressure (SE-IOP) associated with intravitreal injections of anti-vascular endothelial growth factors (anti-VEGF) bevacizumab and aflibercept in patients with wet age-related macular degeneration (wAMD). Methods A… read more here.
Keywords: anti vegf; incidence; bevacizumab aflibercept; intraocular pressure ... See more keywords
Untargeted Metabolomic Study of Patients with Wet Age-Related Macular Degeneration in Aqueous Humor
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s475920
Abstract: Purpose The objective of this study was to ascertain metabolic biomarkers and investigate the metabolic alterations associated with aqueous humor (AH) in wet age-related macular degeneration (AMD). Methods AH samples were collected from a total… read more here.
Keywords: related macular; wet age; wet amd; age related ... See more keywords
Short-Term Effects of Brolucizumab in the Treatment of Wet Age-Related Macular Degeneration or Polypoidal Choroidopathy Refractory to Previous Anti-Vascular Endothelial Growth Factor Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58121703
Abstract: Background and objectives: To report the initial response to a single intravitreal brolucizumab (IVI-B) injection in wet age-related macular degeneration (wAMD) or polypoidal choroidopathy (PCV) complicated with either persistent subretinal fluid (SRF) or pigment epithelial… read more here.
Keywords: wet age; related macular; age related; first ivi ... See more keywords
Preclinical Evaluation of UDCA-Containing Oral Formulation in Mice for the Treatment of Wet Age-Related Macular Degeneration
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11110561
Abstract: As a posterior ocular disease, wet age-related macular degeneration (WAMD) has been known to be related to vision loss, accompanying ocular complications. The intravitreous injection of VEGF antibodies has been reported to be an effective… read more here.
Keywords: age related; related macular; treatment; wet age ... See more keywords