A microhydrodynamic rationale for selection of bead size in preparation of drug nanosuspensions via wet stirred media milling.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.04.001
Abstract: Although wet stirred media milling has proven to be a robust process for producing nanoparticle suspensions of poorly water-soluble drugs and thereby enhancing their bioavailability, selection of bead size has been largely empirical, lacking fundamental… read more here.
Keywords: bead size; wet stirred; drug; size ... See more keywords
Preparation of coconut shell nanoparticles by wet-stirred media milling
Sign Up to like & getrecommendations! Published in 2019 at "Materials Letters"
DOI: 10.1016/j.matlet.2019.126738
Abstract: Abstract Coconut shell nanoparticles have been prepared via top-down approach from wet-stirred media mill. Milling parameters like milling time, feed concentration, effect of surfactants and surfactant concentration have been investigated for efficient production of nanoparticles.… read more here.
Keywords: stirred media; shell nanoparticles; wet stirred; coconut ... See more keywords
Mechanistic Modeling of Wet Stirred Media Milling for Production of Drug Nanosuspensions.
Sign Up to like & getrecommendations! Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01876-w
Abstract: Drug nanocrystals have been used for a wide range of drug delivery platforms in the pharmaceutical industry, especially for bioavailability enhancement of poorly water-soluble drugs. Wet stirred media milling (WSMM) is the most widely used… read more here.
Keywords: stirred media; wet stirred; drug nanosuspensions; mechanistic modeling ... See more keywords