Crystal Structure of Leiomodin 2 in Complex with Actin: A Structural and Functional Reexamination.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.07.007
Abstract: Leiomodins (Lmods) are a family of actin filament nucleators related to tropomodulins (Tmods), which are pointed end-capping proteins. Whereas Tmods have alternating tropomyosin- and actin-binding sites (TMBS1, ABS1, TMBS2, ABS2), Lmods lack TMBS2 and half… read more here.
Keywords: wh2 domain; complex actin; structure;
JMY powers dendritogenesis and is regulated by CaM revealing a general, critical principle in neuromorphogenesis
Sign Up to like & getrecommendations! Published in 2025 at "Communications Biology"
DOI: 10.1038/s42003-025-08208-3
Abstract: Local calcium signals and formation of actin filaments help to steer and power neuronal morphology development and plasticity. Yet, responsible actin nucleators and their linkage to calcium transients largely remained elusive. Here, we identify the… read more here.
Keywords: wh2 domain; principle; jmy; actin ... See more keywords