Nanofibrillar Decellularized Wharton's Jelly Matrix for Segmental Tracheal Repair
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DOI: 10.1002/adfm.201910067
Abstract: Wharton's jelly (WJ) is considered a potential scaffold in tissue‐engineered trachea for its similar composition and function to cartilage tissue. However, the feasibility of using WJ to construct engineered neocartilage tissue has not been reported,… read more here.
Keywords: tissue; tracheal; repair; wharton jelly ... See more keywords
Single‐Cell and Spatial Transcriptomics Decodes Wharton's Jelly‐Derived Mesenchymal Stem Cells Heterogeneity and a Subpopulation with Wound Repair Signatures
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204786
Abstract: The highly heterogeneous characteristics of Wharton's jelly mesenchymal stem cells (WJ‐MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of treatments based on WJ‐MSCs. Exploration of WJ‐MSC heterogeneity with multimodal single‐cell technologies… read more here.
Keywords: subpopulation; cell; heterogeneity; single cell ... See more keywords
Erratum: Human Wharton's Jelly Stem Cells and Its Conditioned Medium Enhance Healing of Excisional and Diabetic Wounds
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26081
Abstract: Wound healing is a major problem in diabetic patients and current treatments have met with limited success. We evaluated the treatment of excisional and diabetic wounds using a stem cell isolated from the human umbilical… read more here.
Keywords: conditioned medium; excisional diabetic; wharton jelly; hwjsc ... See more keywords
Micro‐vesicles derived from human Wharton's Jelly mesenchymal stromal cells mitigate renal ischemia‐reperfusion injury in rats after cardiac death renal transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26348
Abstract: The purpose of the present study was to investigate the possible therapeutic effects of the human Wharton‐Jelly mesenchymal stromal cells derived micro‐vesicles (hWJMSCs‐MVs) on renal ischemia‐reperfusion injury (IRI) after cardiac death (CD) renal transplantation in… read more here.
Keywords: mesenchymal stromal; renal transplantation; wharton jelly; jelly mesenchymal ... See more keywords
Runt‐Related Transcription Factor 2 Induction During Differentiation of Wharton's Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT‐Rich Interactive Domain 1B Histone Demethylase
Sign Up to like & getrecommendations! Published in 2017 at "STEM CELLS"
DOI: 10.1002/stem.2704
Abstract: Novel bone regeneration approaches aim to obtain immature osteoblasts from somatic stem cells. Umbilical cord Wharton's jelly mesenchymal stem cells (WJ‐MSCs) are an ideal source for cell therapy. Hence, the study of mechanisms involved in… read more here.
Keywords: wharton jelly; jelly mesenchymal; differentiation; stem ... See more keywords
Protective effects of CHIP overexpression and Wharton's jelly mesenchymal‐derived stem cell treatment against streptozotocin‐induced neurotoxicity in rats
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23544
Abstract: Diabetic neuropathy is a common complication of diabetes mellitus, posing a challenge in treatment. Previous studies have indicated the protective role of mesenchymal stem cells against several disorders. Although they can repair nerve injury, their… read more here.
Keywords: cell; protective effects; stem; chip ... See more keywords
Effects of polarized and non-polarized red-light irradiation on proliferation of human Wharton's jelly-derived mesenchymal cells.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.09.010
Abstract: Light emitting diode (LED) irradiation has recently been introduced as an encouraging strategy for promotion of cell proliferation. Human umbilical cord Wharton's jelly-derived mesenchymal (hUCM) cells are among the most available mesenchymal cells with a… read more here.
Keywords: irradiation; wharton jelly; red light; proliferation ... See more keywords
Wharton's jelly derived mesenchymal stem cells differentiate into oocyte like cells in vitro by follicular fluid and cumulus cells conditioned medium
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e04992
Abstract: Wharton's jelly derived-mesenchymal stem cells (WJ-MSCs) have a same developmental origin with primordial germ cells. WJ-MSCs perhaps differentiate into oocyte and germ like-cells (OLCs/GLCs) in the presence of appropriate inducers. Human follicular fluid (FF) and… read more here.
Keywords: derived mesenchymal; wharton jelly; differentiate oocyte; jelly derived ... See more keywords
Cycloxygenase-2 inhibition potentiates trans-differentiation of Wharton's jelly-mesenchymal stromal cells into endothelial cells: Transplantation enhances neovascularization-mediated wound repair.
Sign Up to like & getrecommendations! Published in 2019 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2019.01.004
Abstract: BACKGROUND Neo-vascularization, an indispensible phenomenon for tissue regeneration, facilitates repair and remodeling of wound tissues. This process is impaired in chronic wounds due to reduced number and recruitment of endothelial cells (ECs), thereby necessitating development… read more here.
Keywords: mesenchymal stromal; wharton jelly; stromal cells; wound ... See more keywords
Osteogenic potential of Wharton's jelly mesenchymal stromal cells cultured on a biomimetic scaffold
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DOI: 10.1016/j.jcyt.2020.04.083
Abstract: Background & Aim In regenerative medicine, Wharton's jelly mesenchymal stromal cells (WJ-MSCs) have a growing interest in its properties similar to those of bone marrow cells and the immunomodulatory potential. Tissue engineering combines the design… read more here.
Keywords: mesenchymal stromal; wharton jelly; scaffold; stromal cells ... See more keywords
The biomechanics of the umbilical cord Wharton Jelly: Roles in hemodynamic proficiency and resistance to compression.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2019.103377
Abstract: The umbilical cord is a complex structure containing three vessels, one straight vein and two coiled arteries, encased by the Wharton Jelly (WJ) a spongy structure made of collagen and hydrated macromolecules. Fetal blood reaches… read more here.
Keywords: umbilical cord; wharton jelly; cord; biomechanics ... See more keywords