Effects of pre-operant running and sucrose concentration on operant wheel running on a fixed interval schedule of reinforcement.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the experimental analysis of behavior"
DOI: 10.1002/jeab.674
Abstract: Prior research proposed that temporal control over the pattern of operant wheel running on a fixed interval (FI) schedule of sucrose reinforcement is a function of automatic reinforcement generated by wheel running and the experimentally… read more here.
Keywords: operant wheel; schedule; running fixed; reinforcement ... See more keywords
Motivational wheel running reverses cueing behavioural inflexibility in rodents
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-017-1790-z
Abstract: Behavioural inflexibility and associated atypical learning behaviours are common clinical manifestations of the autism spectrum disorder (ASD) phenotype. Despite advances in our understanding of ASD, little research has been devoted to experimental interventions that might… read more here.
Keywords: motivational wheel; inflexibility; running reverses; wheel running ... See more keywords
I Smell a Mouse: Indirect Genetic Effects on Voluntary Wheel-Running Distance, Duration and Speed
Sign Up to like & getrecommendations! Published in 2019 at "Behavior Genetics"
DOI: 10.1007/s10519-018-9930-2
Abstract: Indirect genetic effects (IGEs; the heritable influence of one organism on a conspecific) can affect the evolutionary dynamics of complex traits, including behavior. Voluntary wheel running is an important model system in quantitative genetic studies… read more here.
Keywords: genetic effects; running distance; voluntary wheel; indirect genetic ... See more keywords
Is wheel running a re-directed stereotypic behaviour in striped mice Rhabdomys dilectus?
Sign Up to like & getrecommendations! Published in 2018 at "Applied Animal Behaviour Science"
DOI: 10.1016/j.applanim.2018.04.011
Abstract: Abstract When given the opportunity, many captive animal species make use of a running wheel. Wheel running is often used as an environmental enrichment to increase general locomotor activities. Yet, it is still debated whether… read more here.
Keywords: striped mice; running wheel; wheel running; stereotypic behaviour ... See more keywords
Interleukin 6-independent metabolic reprogramming as a driver of cancer-related fatigue
Sign Up to like & getrecommendations! Published in 2020 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.05.043
Abstract: Fatigue is a common and debilitating symptom of cancer with few effective interventions. Cancer-related fatigue (CRF) is often associated with increases in inflammatory cytokines, however inflammation may not be requisite for this symptom, suggesting other… read more here.
Keywords: metabolic reprogramming; cancer related; related fatigue; cancer ... See more keywords
Deficit in voluntary wheel running in chronic inflammatory and neuropathic pain models in mice: Impact of sex and genotype
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.113009
Abstract: Patients with chronic pain report decreased general activity and emotional distress. Therefore, the development of various animal models that encompass different aspects of pain are crucial for the discovery of genetic differences and the assessment… read more here.
Keywords: neuropathic pain; mice; wheel running; pain ... See more keywords
Environmental enrichment in the absence of wheel running produces beneficial behavioural and anti-oxidative effects in rats
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Processes"
DOI: 10.1016/j.beproc.2017.09.009
Abstract: The effects of early environmental enrichment (EE) when solving a simple spatial task in adult male rats were assessed. After weaning, rats were housed in pairs in enriched or standard cages (EE and control groups)… read more here.
Keywords: absence; absence wheel; environmental enrichment; wheel running ... See more keywords
Automatic reinforcement from operant wheel-running undermines temporal control by fixed-interval schedules of reinforcement
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Processes"
DOI: 10.1016/j.beproc.2018.09.003
Abstract: The current study compared the development of response patterns for operant wheel-running and lever-pressing on fixed-interval schedules. Eleven female Long-Evans rats were exposed to fixed-interval (FI) 15-s, 30-s, and 60-s schedules with wheel revolutions as… read more here.
Keywords: fixed interval; operant wheel; reinforcement; wheel running ... See more keywords
Exercise-Mediated Lowering of Glutamine Availability Suppresses Tumor Growth and Attenuates Muscle Wasting
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DOI: 10.1016/j.isci.2020.100978
Abstract: Summary Glutamine is a central nutrient for many cancers, contributing to the generation of building blocks and energy-promoting signaling necessary for neoplastic proliferation. In this study, we hypothesized that lowering systemic glutamine levels by exercise… read more here.
Keywords: tumor; glutamine availability; wheel running; exercise ... See more keywords
Duration of wheel-running reinforcement: Effects on reinforcement value and motivation in free-feeding and food-deprived rats
Sign Up to like & getrecommendations! Published in 2017 at "Learning and Motivation"
DOI: 10.1016/j.lmot.2017.10.001
Abstract: Abstract Ten (pair housed) female Long-Evans rats were exposed to 5 s, 30 s, and 90 s wheel-running reinforcement durations on a response-initiated variable interval 20 s schedule as food deprivation was manipulated. On free feeding, never-deprived rats showed… read more here.
Keywords: duration; running reinforcement; wheel running; food ... See more keywords
Voluntary wheel running stimulates the expression of Nrf-2 and interleukin-10 but suppresses interleukin-17 in experimental autoimmune encephalomyelitis
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.135382
Abstract: Multiple sclerosis is an inflammatory and neurodegenerative disease of the central nervous system in which the immune cells attack the myelin sheath of the nerves, leading to axonal damage, inflammation, immune cell infiltration, and demyelination… read more here.
Keywords: voluntary wheel; expression nrf; disease; expression ... See more keywords