Loss of cytoplasmic FMR1‐interacting protein 2 (CYFIP2) induces browning in 3T3‐L1 adipocytes via repression of GABA‐BR and activation of mTORC1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30231
Abstract: Obesity and related metabolic disorders are epidemic diseases. Promoting thermogenesis and a functional increase in the browning of white adipocytes may counteract obesity. On the other hand, the molecular mechanism that regulates brown and beige… read more here.
Keywords: cyfip2; cyfip2 induces; white adipocytes; loss ... See more keywords
Reversine promotes browning of white adipocytes by suppressing miR‐133a
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27148
Abstract: Brown adipocytes are characterized by a high number of uncoupling protein 1 (UCP1)‐positive mitochondrial content and increased thermogenic capacity. As UCP1‐enriched cells can consume lipids by generating heat, browning of white adipocytes is now highlighted… read more here.
Keywords: 133a reversine; white adipocytes; mir 133a; browning white ... See more keywords
Anthocyanin oligomers stimulate browning in 3T3‐L1 white adipocytes via activation of the β3‐adrenergic receptor and ERK signaling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7276
Abstract: Microbial fermentation of grape‐skin extracts is found to synthesize anthocyanin oligomers (AO), which are more active than the monomeric anthocyanins that are effective for some metabolic diseases such as diabetes and obesity. This study investigated… read more here.
Keywords: anthocyanin oligomers; white adipocytes; 3t3 white; treatment ... See more keywords
Urolithin A Induces Brown-like Phenotype in 3T3-L1 White Adipocytes via β3-adrenergic Receptor-p38 MAPK Signaling Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-020-0149-8
Abstract: Recently, pharmacological activation of thermogenesis in brown fat and induction of white fat browning (beiging) have been considered as promising strategies in the development of anti-obesity drugs. During the screening of natural compounds that may… read more here.
Keywords: brown like; white adipocytes; 3t3 white; phenotype 3t3 ... See more keywords
Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes
Sign Up to like & getrecommendations! Published in 2020 at "Protein & Cell"
DOI: 10.1007/s13238-020-00717-7
Abstract: Obesity is caused by an imbalance between energy intake and expenditure, and has become a global epidemic with over 650 million adults affected. Adipose tissues in mammals are composed of white adipose tissue (WAT) and… read more here.
Keywords: white adipocytes; beige adipocytes; obesity; ethacrynic acid ... See more keywords
A mechanically activated TRPC1-like current in white adipocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.050
Abstract: Ca2+ impacts a large array of cellular processes in every known cell type. In the white adipocyte, Ca2+ is involved in regulation of metabolic processes such as lipolysis, glucose uptake and hormone secretion. Although the… read more here.
Keywords: white adipocytes; mechanically activated; white adipocyte; ca2 ... See more keywords
Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2017.07.008
Abstract: Objective Obesity-associated WAT inflammation is characterized by the accumulation and local activation of macrophages (MΦs), and recent data from mouse studies suggest that macrophages are modifiers of adipocyte energy metabolism and mitochondrial function. As mitochondrial… read more here.
Keywords: white adipocytes; adipocyte mitochondrial; human adipocyte; metabolism ... See more keywords
Oxidative stress resulting from the removal of endogenous catalase induces obesity by promoting hyperplasia and hypertrophy of white adipocytes
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101749
Abstract: Obesity is regarded as an abnormal expansion and excessive accumulation of fat mass in white adipose tissue. The involvement of oxidative stress in the development of obesity is still unclear. Although mainly present in peroxisomes,… read more here.
Keywords: white adipocytes; cko; obesity; catalase ... See more keywords
Combination of Capsaicin and Capsiate Induces Browning in 3T3-L1 White Adipocytes via Activation of the Peroxisome Proliferator-Activated Receptor γ/β3-Adrenergic Receptor Signaling Pathways.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b02191
Abstract: This study investigated the effects and molecular mechanism of a combination of capsaicin and capsiate on promoting lipid metabolism and inducing browning in 3T3-L1 white adipocytes. The combination significantly suppressed lipid accumulation in adipocytes (… read more here.
Keywords: combination; white adipocytes; combination capsaicin; capsaicin capsiate ... See more keywords
The combined effects of silicon dioxide nanoparticles and cold air exposure on the metabolism and inflammatory responses in white adipocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology research"
DOI: 10.1039/c7tx00145b
Abstract: The potential hazard of nanoparticles (NPs) from air pollution has attracted widespread attention. Though the toxicology of NPs has been intensively studied, few works have been reported on the combined effect of silicon dioxide (SiO2)… read more here.
Keywords: white adipocytes; metabolism; sio2; exposure ... See more keywords
Analysis of the different characteristics between omental preadipocytes and differentiated white adipocytes using bioinformatics methods
Sign Up to like & getrecommendations! Published in 2022 at "Adipocyte"
DOI: 10.1080/21623945.2022.2063471
Abstract: ABSTRACT Obesity is emerging as an epidemiological issue, being associated with the onset and progress of various metabolism-related disorders. Obesity is characterized by the white adipose expansion, which encounters white adipocyte hypertrophy and hyperplasia. White… read more here.
Keywords: white adipocytes; differentiated white; different characteristics; analysis ... See more keywords