Impact of obesity and white adipose tissue inflammation on the omental microenvironment in endometrial cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34356
Abstract: A complex relationship between adipose tissue and malignancy, involving an inflammatory response, has been reported. The goal of this work was to assess the prevalence of white adipose tissue (WAT) inflammation in patients with endometrial… read more here.
Keywords: endometrial cancer; inflammation; adipose tissue; white adipose ... See more keywords
miR‐221 negatively regulates inflammation and insulin sensitivity in white adipose tissue by repression of sirtuin‐1 (SIRT1)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26589
Abstract: It is well known that obesity‐induced white adipose tissue inflammation is an important reason for insulin‐resistance and type 2 diabetes mellitus. Sirtuin‐1 (SIRT1) is an important regulator of inflammtion response pathways in white adipose tissue.… read more here.
Keywords: insulin; mir 221; inflammation; white adipose ... See more keywords
Electroconvulsive seizures lead to lipolytic‐induced gene expression changes in mediobasal hypothalamus and decreased white adipose tissue mass
Sign Up to like & getrecommendations! Published in 2021 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12156
Abstract: Electroconvulsive seizure (ECS) therapy is highly effective in the treatment of several psychiatric disorders, including depression. Past studies have shown that the rodent model of ECS reveals the activation of multiple brain regions including the… read more here.
Keywords: electroconvulsive seizures; hypothalamus; seizures lead; white adipose ... See more keywords
Potato protease inhibitor II prevents obesity by inducing browning of white adipose tissue in mice via β3 adrenergic receptor signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7451
Abstract: There are currently few effective and safe pharmacologic means for inducing beige adipogenesis in humans. This study highlights the role of potato protease inhibitor II (PPI II) in regulating the browning of adipose tissue. The… read more here.
Keywords: protease inhibitor; potato protease; adipose tissue; white adipose ... See more keywords
Human iPSC-Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202203725
Abstract: Chronic white adipose tissue (WAT) inflammation has been recognized as a critical early event in the pathogenesis of obesity-related disorders. This process is characterized by the increased residency of proinflammatory M1 macrophages in WAT. However,… read more here.
Keywords: microphysiological system; ipsc derived; adipose tissue; white adipose ... See more keywords
Nutmeg extract potentially alters characteristics of white adipose tissue in rats
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.383
Abstract: Abstract Background Browning of white adipose tissue (WAT) is a promising approach to obesity treatment. During browning, WAT transforms into beige adipose tissue through stimulation of the peroxisome proliferator activated receptor γ (PPARγ). Nutmeg, one… read more here.
Keywords: even though; wat; white adipose; potentially alters ... See more keywords
Insights from Studies of White Adipose Tissue Using Single-Cell Approaches.
Sign Up to like & getrecommendations! Published in 2022 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2021_578
Abstract: Technologies allowing studies at single-cell resolution have provided important insights into how different cell populations contribute to tissue function. Application of these methods to white adipose tissue (WAT) has revealed how various metabolic aspects of… read more here.
Keywords: single cell; tissue; insights studies; adipose tissue ... See more keywords
Role of Ginsenosides in Browning of White Adipose Tissue to Combat Obesity: A Narrative Review on Molecular Mechanism.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2021.11.003
Abstract: BACKGROUND AND AIMS Adipose tissue play an important role in the regulation of energy balance and homeostasis. Two main types of adipose tissue are found in mammals, white adipose tissue (WAT) and brown adipose tissue… read more here.
Keywords: obesity; white adipose; role ginsenosides; adipose tissue ... See more keywords
Systemic inhibition of Janus kinase induces browning of white adipose tissue and ameliorates obesity-related metabolic disorders.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.05.131
Abstract: Browning of white adipose tissue is a promising strategy to tackle obesity. Recently, Janus kinase (JAK) inhibition was shown to induce white-to-brown metabolic conversion of adipocytes in vitro; however effects of JAK inhibition on browning and… read more here.
Keywords: inhibition; white adipose; adipose tissue; obesity ... See more keywords
The novel adipokine CTRP5 is a negative regulator of white adipose tissue browning.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.01.111
Abstract: The browning of white adipose tissue predominantly emerges as an adaptation to environmental cues, such as cold exposure. The enhanced browning of adipose tissue results in improved energy and glucose homeostasis and reduced fat mass… read more here.
Keywords: ctrp5; white adipose; tissue; tissue browning ... See more keywords
Cold-Induced Browning of Inguinal White Adipose Tissue Is Independent of Adipose Tissue Cyclooxygenase-2.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.06.082
Abstract: Previous studies using genetic mouse models have implicated COX-2 in the browning of white adipose tissues (WATs) in mice during cold exposure. However, COX-2 is important during development, and conventional knockouts (KOs) exhibit many defects,… read more here.
Keywords: browning inguinal; white adipose; tissue; cox ... See more keywords