Could Egg White Lysozyme be Solved by Single Particle Cryo-EM?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.9b01176
Abstract: The combination of high-end cryogenic transmission electron microscopes (cryo-EM), direct electron detectors, and advanced image algorithms allows researchers to obtain the 3D structures of much smaller macromolecules than years ago. However, there are still major… read more here.
Keywords: particle; particle cryo; white lysozyme; egg white ... See more keywords
Does poly(ionic liquid) modulate the non-covalent interactions of chicken egg white lysozyme? Elucidation of biomolecular interactions between biomolecules and macromolecular solvents
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c9nj04078a
Abstract: Stabilizing and destabilizing effects of different poly(ionic liquid) (PIL) concentrations on chicken egg white lysozyme as a reason for bimolecular interactions. read more here.
Keywords: ionic liquid; chicken egg; white lysozyme; poly ionic ... See more keywords
Methylglyoxal modification reduces the sensitivity of hen egg white lysozyme to stress-induced aggregation: Insight into the anti-amyloidogenic property of α-dicarbonyl compound
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2019.1702589
Abstract: Abstract The reactive α-oxoaldehyde, methylglyoxal reacts with different proteins to form Advanced Glycation End Products (AGEs) through Maillard reaction. Its level increases significantly in diabetic condition. Here, we have investigated the effect of different concentrations… read more here.
Keywords: methylglyoxal modification; hen egg; methylglyoxal; white lysozyme ... See more keywords
Unit-cell response of tetragonal hen egg white lysozyme upon controlled relative humidity variation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Crystallography"
DOI: 10.1107/s1600576719009919
Abstract: Variation of relative humidity (rH) greatly affects the internal order of solvent-based protein crystals, and the rearrangement of molecules can be efficiently recorded in distinct diffraction patterns. This study focuses on this topic, reporting the… read more here.
Keywords: hen egg; egg white; variation; white lysozyme ... See more keywords
Molecular dynamics study on the effects of charged amino acid distribution under low pH condition to the unfolding of hen egg white lysozyme and formation of beta strands
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0249742
Abstract: Aggregation of unfolded or misfolded proteins into amyloid fibrils can cause various diseases in humans. However, the fibrils synthesized in vitro can be developed toward useful biomaterials under some physicochemical conditions. In this study, atomistic… read more here.
Keywords: white lysozyme; hen egg; molecular dynamics; beta strand ... See more keywords
Study the Interaction of Ni Complex of Tetradentate Schiff Base Ligand with HEN Egg White Lysozyme
Sign Up to like & getrecommendations! Published in 2017 at "Physical Chemistry Research"
DOI: 10.22036/pcr.2017.38593
Abstract: Interaction of Ni complex (Salen = N,N´-ethylene bis (salicylideneimine)) with hen egg white lysozyme (HEWL) was studied by absorption spectroscopy, competitive binding study and thermal denaturation study. The protein binding affinity of Ni complex was… read more here.
Keywords: study; hen egg; interaction complex; white lysozyme ... See more keywords
Roles of Tryptophan and Charged Residues on the Polymorphisms of Amyloids Formed by K-Peptides of Hen Egg White Lysozyme Investigated through Molecular Dynamics Simulations
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032626
Abstract: Atomistic molecular dynamics simulations of amyloid models, consisting of the previously reported STDY-K-peptides and K-peptides from the hen egg white lysozyme (HEWL), were performed to address the effects of charged residues and pH observed in… read more here.
Keywords: dynamics simulations; egg white; peptides hen; molecular dynamics ... See more keywords
Insights on Aggregation of Hen Egg-White Lysozyme from Raman Spectroscopy and MD Simulations
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27207122
Abstract: Protein misfolding and aggregation play a significant role in several neurodegenerative diseases. In the present work, the spontaneous aggregation of hen egg-white lysozyme (HEWL) in an alkaline pH 12.2 at an ambient temperature was studied… read more here.
Keywords: aggregation; egg white; spectroscopy; hen egg ... See more keywords