A peptide inhibitor of macrophage migration in atherosclerosis purified from the leech Whitmania pigra.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.112723
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Atherosclerosis has become a worldwide public health problem that seriously threatens human health. Leech is traditional Chinese medicine that can be utilized to treat cardiovascular disease. Based on the anti-atherosclerosis activity of leech… read more here.
Keywords: macrophage migration; leech whitmania; leech peptide; migration ... See more keywords
Life without blood: Molecular and functional analysis of hirudins and hirudin‐like factors of the Asian non‐hematophagous leech Whitmania pigra
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15762
Abstract: Several leech species of the genera Hirudo, Hirudinaria, and Whitmania are widely used in traditional Chinese medicine (TCM) for the oral treatment of disorders associated with blood stasis. Among them, the non‐hematophagous leech Whitmania pigra… read more here.
Keywords: hematophagous leech; whitmania; non hematophagous; whitmania pigra ... See more keywords
Whitmania Pigra Whitman Extracts Inhibit Lipopolysaccharide Induced Rat Vascular Smooth Muscle Cells Migration and their Adhesion Ability to THP-1 and RAW 264.7 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Atherosclerosis and Thrombosis"
DOI: 10.5551/jat.36558
Abstract: Aim: Atherosclerosis is a kind of chronic inflammatory disease. A crucial pathology change of atherosclerosis is the migration of activated VSMCs to the intima where they interact with leukocytes by expressing adhesion molecules, including intercellular… read more here.
Keywords: vsmcs; adhesion; migration; whitmania pigra ... See more keywords