Getting the whole picture: High content screening using three‐dimensional cellular model systems and whole animal assays
Sign Up to like & getrecommendations! Published in 2017 at "Cytometry Part A"
DOI: 10.1002/cyto.a.22907
Abstract: Phenotypic or High Content Screening (HCS) is becoming more widely used for primary screening campaigns in drug discovery. Currently the vast majority of HCS campaigns are using cell lines grown in well‐established monolayer cultures (2D… read more here.
Keywords: animal assays; tissue culture; whole animal; content screening ... See more keywords
Life in the freezer: protein metabolism in Antarctic fish
Sign Up to like & getrecommendations! Published in 2022 at "Royal Society Open Science"
DOI: 10.1098/rsos.211272
Abstract: Whole-animal, in vivo protein metabolism rates have been reported in temperate and tropical, but not Antarctic fish. Growth in Antarctic species is generally slower than lower latitude species. Protein metabolism data for Antarctic invertebrates show… read more here.
Keywords: growth; protein metabolism; antarctic fish; whole animal ... See more keywords
PyKleeBarcode: Enabling representation of the whole animal kingdom in information space
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0286314
Abstract: As biological sequence databases continue growing, so do the insight that they promise to shed on the shape of the genetic diversity of life. However, to fulfil this promise the software must remain usable, be… read more here.
Keywords: enabling representation; pykleebarcode; whole animal; representation whole ... See more keywords
Characterization of perfusion decellularized whole animal body, isolated organs, and multi‐organ systems for tissue engineering applications
Sign Up to like & getrecommendations! Published in 2021 at "Physiological Reports"
DOI: 10.14814/phy2.14817
Abstract: To expand the application of perfusion decellularization beyond isolated single organs, we used the native vasculature of adult and neonatal rats to systemically decellularize the organs of a whole animal in situ. Acellular scaffolds were… read more here.
Keywords: perfusion decellularized; organ systems; whole animal; animal body ... See more keywords