Articles with "whole blood" as a keyword



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Whole-Blood Gene Expression Profile After Hypoxic-Ischemic Encephalopathy

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Published in 2024 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2023.54433

Abstract: This case-control study compares the genome expression at birth and associated outcome in neonates with hypoxic-ischemic encephalopathy in a high-income country (Italy) and their counterparts in low- to middle-income countries (India, Sri Lanka, and Bangladesh). read more here.

Keywords: whole blood; gene expression; hypoxic ischemic; blood gene ... See more keywords

Incorrect Data Used in Statistical Analyses.

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Published in 2017 at "JAMA neurology"

DOI: 10.1001/jamaneurol.2016.6106

Abstract: Incorrect Data Used in Statistical Analyses To the Editor On behalf of our coauthors, we write to explain errors that occurred in our article, “Association of Environmental Toxins With Amyotrophic Lateral Sclerosis,” which was published… read more here.

Keywords: neurology; statistical analyses; plasma; article ... See more keywords

Use of Uncrossmatched Cold-Stored Whole Blood in Injured Children With Hemorrhagic Shock

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Published in 2018 at "JAMA Pediatrics"

DOI: 10.1001/jamapediatrics.2017.5238

Abstract: This study compares the time to transfusion in traumatically injured children receiving uncrossmatched whole blood with time to infusion in a historical cohort that received blood components. read more here.

Keywords: cold stored; use uncrossmatched; injured children; blood ... See more keywords

Mechano‐Lysis in Whole Blood Clots: On How Mechanics Affect Clot Lysis, and How Lysis Affects Clot Mechanics

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202403389

Abstract: Thromboembolic diseases are a significant cause of mortality and are clinically treated enzymatically with tissue plasminogen activator (tPA). Interestingly, prior studies in fibrin fibers and fibrin gels have demonstrated that thrombolysis may be mechanically sensitive.… read more here.

Keywords: blood clots; whole blood; clot; mechanics ... See more keywords

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202508185

Abstract: Babesiosis – a globally emerging tick‐borne infectious disease primarily caused by the intraerythrocytic piroplasm parasite, Babesia microti – has traditionally been studied using animal models such as mice. Compared to animal models, microfluidic‐based models offer… read more here.

Keywords: whole blood; infection dynamics; blood; babesia microti ... See more keywords
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Whole blood viscosity and red blood cell adhesion: Potential biomarkers for targeted and curative therapies in sickle cell disease

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Published in 2020 at "American Journal of Hematology"

DOI: 10.1002/ajh.25933

Abstract: Sickle cell disease (SCD) is a recessive genetic blood disorder exhibiting abnormal blood rheology. Polymerization of sickle hemoglobin, due to a point mutation in the β‐globin gene of hemoglobin, results in aberrantly adhesive and stiff… read more here.

Keywords: rbc adhesion; rheology; adhesion; blood ... See more keywords

Extraction of Cell-Free Whole Blood Plasma Using a Dielectrophoresis-Based Microfluidic Device.

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Published in 2019 at "Biotechnology journal"

DOI: 10.1002/biot.201800181

Abstract: Blood is the most valuable and convenient source of disease diagnostic biomarkers, but plasma must be extracted from blood prior to further biomarker detection and analysis. Traditional plasma extraction methods depend greatly on benchtop equipment… read more here.

Keywords: extraction; plasma extraction; blood; whole blood ... See more keywords

Flow cytometric kinetic assay of calcium mobilization in whole blood platelets of bottlenose dolphins (Tursiops truncatus)

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Published in 2022 at "Cytometry Part A"

DOI: 10.1002/cyto.a.24693

Abstract: Marine mammals may suffer alterations in platelet function and hemostasia due to multiple pathologies, environmental conditions (including stress) or exposure to different contaminants that induce platelet activation. Detecting early alterations in platelet function in these… read more here.

Keywords: platelet activation; kinetic assay; whole blood; bottlenose dolphins ... See more keywords

OMIP‐107: 8‐color whole blood immunophenotyping panel for the characterization and quantification of lymphocyte subsets and monocytes in swine

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Published in 2024 at "Cytometry Part A"

DOI: 10.1002/cyto.a.24897

Abstract: We developed this whole blood immunophenotyping panel with the aim to monitor and quantify major lymphocyte subsets (CD4+, CD8+, CD4+CD8+ αβ T cells, γδ‐T cells, B and NK cells) and monocytes in pigs. The panel… read more here.

Keywords: lymphocyte subsets; immunophenotyping panel; panel; blood immunophenotyping ... See more keywords
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Low-volume LC-MS/MS method for the pharmacokinetic investigation of carvedilol, enalapril and their metabolites in whole blood and plasma: application to a paediatric clinical trial.

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Published in 2020 at "Drug testing and analysis"

DOI: 10.1002/dta.2949

Abstract: Evidence-based pharmacotherapy with carvedilol and enalapril in children suffering from heart failure is insufficient owing to limited pharmacokinetic data.1 While a few datasets regarding enalapril, its metabolite enalaprilat and carvedilol in children have been published,… read more here.

Keywords: carvedilol; blood; whole blood; blood plasma ... See more keywords

Whole blood transcriptomic profiling identifies molecular pathways related to cardiovascular mortality in heart failure

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Published in 2022 at "European Journal of Heart Failure"

DOI: 10.1002/ejhf.2540

Abstract: Chronic heart failure (CHF) is a systemic syndrome with a poor prognosis and a need for novel therapies. We investigated whether whole blood transcriptomic profiling can provide new mechanistic insights into cardiovascular (CV) mortality in… read more here.

Keywords: blood transcriptomic; heart failure; transcriptomic profiling; whole blood ... See more keywords