Reciprocal Translocation Analysis with Whole Chromosome Painting for FISH.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9432-8_14
Abstract: Ionizing radiation can produce many chromosome aberrations; however, a number of aberrations are not readily detectable with a conventional Giemsa staining and require special staining methods. Moreover, an easy method to identify nondetectable chromosomal aberrations,… read more here.
Keywords: whole chromosome; chromosome painting; translocation analysis; analysis whole ... See more keywords
8. SEGMENTAL ANEUPLOIDIES SHOW MOSAIC PATTERN REDUCING PREDICTIVE VALUE COMPARED TO HIGH WHOLE CHROMOSOME ANEUPLOIDIES REPRESENTATIVENESS
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive BioMedicine Online"
DOI: 10.1016/j.rbmo.2019.04.043
Abstract: Introduction The introduction of highly sensitive Next Generation Sequencing (NGS) platforms for PGT-A applications concurred with an increased detection of segmental aneuploidies. Recent studies focused on understanding whether segmental aneuploidies derive from mitotic or meiotic… read more here.
Keywords: whole chromosome; chromosome; predictive value; segmental aneuploidies ... See more keywords
Assembly of whole-chromosome pseudomolecules for polyploid plant genomes using outbred mapping populations.
Sign Up to like & getrecommendations! Published in 2020 at "Nature genetics"
DOI: 10.1038/s41588-020-00717-7
Abstract: Despite advances in sequencing technologies, assembly of complex plant genomes remains elusive due to polyploidy and high repeat content. Here we report PolyGembler for grouping and ordering contigs into pseudomolecules by genetic linkage analysis. Our… read more here.
Keywords: whole chromosome; mapping; plant; plant genomes ... See more keywords
Whole-chromosome paints in maize reveal rearrangements, nuclear domains, and chromosomal relationships
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1813957116
Abstract: Significance Whole-chromosome oligo-FISH paints using synthetic oligonucleotide libraries that can be amplified and labeled were generated for all 10 chromosomes of maize, facilitating chromosome studies with high sensitivity and specificity for genetically diverse lines. Applications… read more here.
Keywords: paints maize; whole chromosome; chromosomal relationships; chromosome paints ... See more keywords
Chromosome instability in neuroblastoma: A pathway to aggressive disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.988972
Abstract: For over 100-years, genomic instability has been investigated as a central player in the pathogenesis of human cancer. Conceptually, genomic instability includes an array of alterations from small deletions/insertions to whole chromosome alterations, referred to… read more here.
Keywords: chromosome instability; instability; chromosome; chromosome aneuploidy ... See more keywords