Morphology-Based Whole Embryo Culture for Developmental Toxicity of Drugs.
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DOI: 10.1007/978-1-4939-7883-0_8
Abstract: In vivo pregnant study protocols covering preconceptional exposure as well as prenatal and postnatal development including the lactation period to screen the toxic effects on specific elements of the highly complicated reproductive cycle are time-consuming… read more here.
Keywords: embryo culture; based whole; developmental toxicity; whole embryo ... See more keywords
xNgn2 induces expression of predominantly sensory neuron markers in Xenopus whole embryo ectoderm but induces mixed subtype expression in isolated ectoderm explants
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DOI: 10.12688/wellcomeopenres.14911.1
Abstract: Proneural basic-helix-loop-helix (bHLH) proteins, such as Neurogenin2 (Ngn2) and Ascl1, are critical regulators at the onset of neuronal differentiation. Endogenously they have largely complementary expression patterns, and have conserved roles in the specification of distinct… read more here.
Keywords: neuron markers; embryo; expression; motor ... See more keywords