Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.6b00916
Abstract: The underlying molecular mechanisms of autoimmune diseases are poorly understood. To unravel the autoimmune processes across diseases, comprehensive and unbiased analyses of proteins targets recognized by the adaptive immune system are needed. Here we present… read more here.
Keywords: autoantibody repertoires; multiple sclerosis; whole proteome; peptide microarrays ... See more keywords
Prot-SpaM: fast alignment-free phylogeny reconstruction based on whole-proteome sequences
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DOI: 10.1093/gigascience/giy148
Abstract: Abstract Word-based or ‘alignment-free’ sequence comparison has become an active research area in bioinformatics. While previous word-frequency approaches calculated rough measures of sequence similarity or dissimilarity, some new alignment-free methods are able to accurately estimate… read more here.
Keywords: whole proteome; spam fast; proteome sequences; prot spam ... See more keywords
Immunoinformatic analysis of the whole proteome for vaccine design: An application to Clostridium perfringens
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.942907
Abstract: Clostridium perfringens is a dangerous bacterium and known biological warfare weapon associated with several diseases, whose lethal toxins can produce necrosis in humans. However, there is no safe and fully effective vaccine against C. perfringens… read more here.
Keywords: immunoinformatic analysis; vaccine; whole proteome; clostridium perfringens ... See more keywords
Evaluation of the Whole Proteome of Achromobacter xylosoxidans to Identify Vaccine Targets for mRNA and Peptides-Based Vaccine Designing Against the Emerging Respiratory and Lung Cancer-Causing Bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.825876
Abstract: Achromobacter xylosoxidans is a rod-shaped Gram-negative bacterium linked with causing several infections which mostly includes hematological malignancies. It has been recently reported to be associated with the development and progression of lung cancer and is… read more here.
Keywords: achromobacter xylosoxidans; vaccine targets; vaccine designing; whole proteome ... See more keywords