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   Articles with "whole proteome" as a keyword



Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.

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recommendations! Published in 2017 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.6b00916

Abstract: The underlying molecular mechanisms of autoimmune diseases are poorly understood. To unravel the autoimmune processes across diseases, comprehensive and unbiased analyses of proteins targets recognized by the adaptive immune system are needed. Here we present… read more here.

Keywords: autoantibody repertoires; multiple sclerosis; whole proteome; peptide microarrays ... See more keywords

Whole proteome screening to develop a potent epitope-based vaccine against Coxiella burnetii: a reverse vaccinology approach

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recommendations! Published in 2024 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2024.2326198

Abstract: Abstract Coxiellosis is known as a threat to human health. This study aimed to develop an epitope-based vaccine against coxiellosis using a whole proteome investigation. In this case, the whole proteome of Coxiella burnetii was… read more here.

Keywords: based vaccine; developed vaccine; epitope based; whole proteome ... See more keywords

Prot-SpaM: fast alignment-free phylogeny reconstruction based on whole-proteome sequences

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recommendations! Published in 2019 at "GigaScience"

DOI: 10.1093/gigascience/giy148

Abstract: Abstract Word-based or ‘alignment-free’ sequence comparison has become an active research area in bioinformatics. While previous word-frequency approaches calculated rough measures of sequence similarity or dissimilarity, some new alignment-free methods are able to accurately estimate… read more here.

Keywords: whole proteome; spam fast; proteome sequences; prot spam ... See more keywords

Immunoinformatic analysis of the whole proteome for vaccine design: An application to Clostridium perfringens

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.942907

Abstract: Clostridium perfringens is a dangerous bacterium and known biological warfare weapon associated with several diseases, whose lethal toxins can produce necrosis in humans. However, there is no safe and fully effective vaccine against C. perfringens… read more here.

Keywords: immunoinformatic analysis; vaccine; whole proteome; clostridium perfringens ... See more keywords

Evaluation of the Whole Proteome of Achromobacter xylosoxidans to Identify Vaccine Targets for mRNA and Peptides-Based Vaccine Designing Against the Emerging Respiratory and Lung Cancer-Causing Bacteria

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recommendations! Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2021.825876

Abstract: Achromobacter xylosoxidans is a rod-shaped Gram-negative bacterium linked with causing several infections which mostly includes hematological malignancies. It has been recently reported to be associated with the development and progression of lung cancer and is… read more here.

Keywords: achromobacter xylosoxidans; vaccine targets; vaccine designing; whole proteome ... See more keywords