Quantitative differentiation of whole smoke solution‐induced mutagenicity in the mouse lymphoma assay
Sign Up to like & getrecommendations! Published in 2018 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22151
Abstract: In vitro genotoxicity dose–response data have been investigated for their utility in modeling and assessing potential differences in mutagenic responses between machine‐generated whole smoke solutions (WSSs) from combusted cigarette tobacco products. Our previous study observed… read more here.
Keywords: whole smoke; potency; mouse lymphoma; lymphoma assay ... See more keywords
Cigarette whole smoke solutions disturb mucin homeostasis in a human in vitro airway tissue model.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology"
DOI: 10.1016/j.tox.2018.07.015
Abstract: Many cigarette smoke-associated airway diseases involve alterations in mucin homeostasis. With the rationale that relevant tissue responses can be measured to evaluate the adverse health effects of tobacco products, we assessed changes in mucin secretion… read more here.
Keywords: whole smoke; airway tissue; tissue model; smoke ... See more keywords
Cytotoxicity, oxidative stress, and inflammatory response of smokeless tobacco extracts and cytotoxicity of combustible cigarette whole smoke in a 3D oral organotypic buccal cell model.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology mechanisms and methods"
DOI: 10.1080/15376516.2021.2009949
Abstract: Oral disease is frequently associated with viral and environmental exposures and oral hygiene. The use of tobacco is a risk factor in the development of oral disease. Cytotoxicity, inflammatory response, and oxidative stress have been… read more here.
Keywords: whole smoke; oxidative stress; tobacco; cytotoxicity ... See more keywords