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   Articles with "whole transcriptome" as a keyword



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Application of a Neural Network Whole Transcriptome–Based Pan-Cancer Method for Diagnosis of Primary and Metastatic Cancers

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recommendations! Published in 2019 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2019.2597

Abstract: This cross-sectional diagnostic study evaluates the accuracy of a machine learning method that uses the whole transcriptome to identify gene markers in primary and metastatic tumors. read more here.

Keywords: whole transcriptome; network whole; primary metastatic; neural network ... See more keywords
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Optimized Whole Transcriptome Profiling of Motor Axons.

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recommendations! Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7231-9_16

Abstract: In highly polarized cells such as neurons, most RNA molecules are not randomly distributed but sorted into different compartments. So far, methods to analyze the transcriptome in distinct subcellular compartments are not well established. Here,… read more here.

Keywords: whole transcriptome; motor axons; transcriptome; transcriptome profiling ... See more keywords
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Establishment of a lncRNA-miRNA-mRNA network in a rat model of atrial fibrosis by whole transcriptome sequencing

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recommendations! Published in 2022 at "Journal of Interventional Cardiac Electrophysiology"

DOI: 10.1007/s10840-022-01120-4

Abstract: Dysregulation of long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) plays important roles in atrial fibrillation (AF). This study aimed to identify crucial lncRNAs, miRNAs, and mRNAs in AF based on whole transcriptome sequencing. Thirty Sprague… read more here.

Keywords: transcriptome sequencing; whole transcriptome; atrial fibrosis; model ... See more keywords
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Whole transcriptome-based ceRNA network analysis revealed ochratoxin A-induced compromised intestinal tight junction proteins through WNT/Ca2+ signaling pathway.

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recommendations! Published in 2021 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2021.112637

Abstract: Ochratoxin A (OTA) is a widespread environmental pollutant that is a threat to humans and livestock and remains a global concern to public health. It has negative effects on both humans and animals that are… read more here.

Keywords: whole transcriptome; intestinal barrier; analysis; wnt ca2 ... See more keywords
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Re: Prediction of Lymph Node Metastasis in Patients with Bladder Cancer Using Whole Transcriptome Gene Expression Signatures.

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recommendations! Published in 2017 at "European urology"

DOI: 10.1016/j.eururo.2017.01.005

Abstract: Expert’s summary: Seiler and colleagues recently published a 51-gene signature (KNN51) comprising coding and noncoding transcripts that allows prediction of lymph node (LN) metastases in patients with muscle-invasive bladder cancer (MIBC). To generate their new… read more here.

Keywords: bladder cancer; whole transcriptome; lymph node; gene ... See more keywords
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Whole transcriptome sequencing analyses of DHA treated glioblastoma cells

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recommendations! Published in 2019 at "Journal of the Neurological Sciences"

DOI: 10.1016/j.jns.2018.11.027

Abstract: Glioblastoma (GBM) is a typical malignant tumor, and there are no effective drugs capable of improving patient survival. Docosahexaenoic acid (DHA), a nutrient essential to animal health and neurodevelopment, exerts an anticancer effect in several… read more here.

Keywords: glioblastoma; whole transcriptome; gbm; cells whole ... See more keywords
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De novo assembly and annotation of the whole transcriptome of Sepiella maindroni

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recommendations! Published in 2017 at "Marine Genomics"

DOI: 10.1016/j.margen.2017.06.004

Abstract: Abstract As an important cephalopods species, Sepiella maindroni fishery has suffered a severe decline due to over-fishing since the 1980s. Stock enhancement has been applied to the resource recovery of this species, but a sexual… read more here.

Keywords: annotation; whole transcriptome; novo assembly; sepiella maindroni ... See more keywords
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Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons

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recommendations! Published in 2017 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2017.08.014

Abstract: RNA binding motif 5 (RBM5) is a nuclear protein that modulates gene transcription and mRNA splicing in cancer cells. The brain is among the highest RBM5-expressing organ in the body but its mRNA target(s) or… read more here.

Keywords: rbm5 neurons; whole transcriptome; rab4a; transcriptome microarray ... See more keywords
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Whole transcriptome analysis reveals the key genes and noncoding RNAs related to follicular atresia in broilers.

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recommendations! Published in 2022 at "Animal biotechnology"

DOI: 10.1080/10495398.2022.2136680

Abstract: Broodiness, a maternal behavior, is accompanied by the atresia of follicles and the serious degradation of poultry reproductive performance. The comparison of follicles between brooding and laying hens is usually an ideal model for exploring… read more here.

Keywords: whole transcriptome; expressed follicles; follicles brooding; laying hens ... See more keywords
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Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex

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recommendations! Published in 2017 at "Cerebral Cortex"

DOI: 10.1093/cercor/bhv346

Abstract: Abstract Focal cortical dysplasias (FCDs) are local malformations of the human neocortex with strong epileptogenic potential. To investigate the underlying pathomechanisms, we performed a whole human transcriptome screening to compare the gene expression pattern of… read more here.

Keywords: whole transcriptome; myelin; temporal neocortex; screening reveals ... See more keywords
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Whole Transcriptome Sequencing Reveals Core Genes Related to Spermatogenesis in Bactrian Camels.

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recommendations! Published in 2023 at "Journal of animal science"

DOI: 10.1093/jas/skad115

Abstract: Bactrian camels survive and reproduce better in extreme climatic conditions than other domestic animals can. However, the reproductive efficiency of camels under their natural pastoral conditions is low. Several factors affect mammalian reproductive performance, including… read more here.

Keywords: spermatogenesis; whole transcriptome; differential expressed; bactrian camel ... See more keywords