Genome‐wide analysis of the mouse LIM gene family reveals its roles in regulating pathological cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Letters"
DOI: 10.1002/1873-3468.14168
Abstract: LIM‐domain proteins have been shown to be associated with heart development and diseases. Systematic studies of LIM family members at the genome‐wide level, which are crucial to further understand their functions in cardiac hypertrophy, are… read more here.
Keywords: genome wide; cardiac hypertrophy; analysis mouse; family ... See more keywords
Affinity-Based Enrichment Techniques for the Genome-Wide Analysis of 5-Hydroxymethylcytosine.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7481-8_35
Abstract: Since its initial characterization in 2009 there has been a great degree of interest in comparative profiling of 5-hydroxymethylcytosine (5hmC) nucleotides in vertebrate DNA. Through a host of genome-wide studies the distribution of 5hmC has… read more here.
Keywords: genome wide; enrichment; affinity; wide analysis ... See more keywords
Genome-wide analysis reveals the evolution and structural features of WRINKLED1 in plants
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Genetics and Genomics"
DOI: 10.1007/s00438-018-1512-8
Abstract: WRINKLED1 (WRI1), an AP2/ERE transcription factor, is one of the most important regulators of oil accumulation. It has been extensively studied in angiosperms, but its evolution and overview features in plants remain unknown. In this… read more here.
Keywords: analysis reveals; genome wide; evolution; vascular plants ... See more keywords
Genome-wide analysis of the abiotic stress-related bZIP family in switchgrass
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05561-w
Abstract: The large basic leucine zipper (bZIP) transcription factor family is conserved in plants. These proteins regulate growth, development, and stress response. Here, we conducted a genome-wide analysis to identify the bZIP genes associated with stress… read more here.
Keywords: genome wide; analysis; switchgrass; family ... See more keywords
Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.07.083
Abstract: ADP-ribosylation (ADPr) is a reversible posttranslational modification involved in a range of cellular processes. Here, we report system-wide identification of serine ADPr in human cells upon oxidative stress. High-resolution mass spectrometry and unrestricted data processing… read more here.
Keywords: adpr; adp ribosylation; serine; wide analysis ... See more keywords
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.12.019
Abstract: The human genome harbors 14,000 duplicated or retroposed pseudogenes. Given their functionality as regulatory RNAs and low conservation, we hypothesized that pseudogenes could shape human-specific phenotypes. To test this, we performed co-expression analyses and found… read more here.
Keywords: genome wide; thalassemia; wide analysis; analysis pseudogenes ... See more keywords
Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13585-5
Abstract: Socioeconomic position (SEP) is a multi-dimensional construct reflecting (and influencing) multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 participants from UK Biobank, we identify 30 (29 previously unreported) independent-loci associated with income.… read more here.
Keywords: genome wide; associated income; wide analysis; loci associated ... See more keywords
Epigenome-wide Analysis Identifies Genes and Pathways Linked to Neurobehavioral Variation in Preterm Infants
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42654-4
Abstract: Neonatal molecular biomarkers of neurobehavioral responses (measures of brain-behavior relationships), when combined with neurobehavioral performance measures, could lead to better predictions of long-term developmental outcomes. To this end, we examined whether variability in buccal cell… read more here.
Keywords: analysis identifies; age; wide analysis; preterm infants ... See more keywords
Genome-wide analysis of genetic variations between dominant and recessive NILs of glanded and glandless cottons
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45454-y
Abstract: Cotton is an important economic crop in worldwide. It produces fiber for the textile industry and provides cottonseeds with high-quality protein and oil. However, the presence of gossypol limits the utilization of cottonseed. Two pairs… read more here.
Keywords: genome wide; coker 312; recessive nils; dominant recessive ... See more keywords
Genome-wide analysis reveals novel regulators of synaptic maintenance in Drosophila
Sign Up to like & getrecommendations! Published in 2023 at "Genetics"
DOI: 10.1093/genetics/iyad025
Abstract: Abstract Maintaining synaptic communication is required to preserve nervous system function as an organism ages. While much work has been accomplished to understand synapse formation and development, we understand relatively little regarding maintaining synaptic integrity… read more here.
Keywords: maintenance; synaptic maintenance; genome wide; drosophila ... See more keywords
Genome-Wide Analysis and Expression Profiles of the MYB Genes in Brachypodium distachyon
Sign Up to like & getrecommendations! Published in 2017 at "Plant and Cell Physiology"
DOI: 10.1093/pcp/pcx115
Abstract: MYB transcription factors are widespread in plants and play key roles in plant development. Although MYB transcription factors have been thoroughly characterized in many plants, genome-wide analysis of the MYB gene family has not yet… read more here.
Keywords: genome wide; bdmyb genes; analysis; wide analysis ... See more keywords