An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
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DOI: 10.1016/j.cell.2018.03.052
Abstract: Resistance to chemotherapy plays a significant role in cancer mortality. To identify genetic units affecting sensitivity to cytarabine, the mainstay of treatment for acute myeloid leukemia (AML), we developed a comprehensive and integrated genome-wide platform based on… read more here.
Keywords: genome wide; non coding; wide crispra; resistance ... See more keywords