Epigenome-wide DNA methylation analysis of myasthenia gravis.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13656
Abstract: Myasthenia gravis (MG) is a common neuromuscular junction (NMJ) disorder and autoimmune disease mediated by several antibodies. Several studies have shown that genetic factors play an important role in MG pathogenesis. To gain insight into… read more here.
Keywords: methylation; methylation analysis; dna methylation; wide dna ... See more keywords
Functional correlation of genome‐wide DNA methylation profiles in genetic neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24446
Abstract: An expanding range of genetic syndromes are characterized by genome‐wide disruptions in DNA methylation profiles referred to as episignatures. Episignatures are distinct, highly sensitive, and specific biomarkers that have recently been applied in clinical diagnosis… read more here.
Keywords: methylation; methylation profiles; dna methylation; genome wide ... See more keywords
Endometrial genome-wide DNA methylation patterns of Guanzhong dairy goats at days 5 and 15 of the gestation period.
Sign Up to like & getrecommendations! Published in 2019 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2019.106124
Abstract: Uterine receptivity for the embryo is established and maintained through a series of precise cellular and molecular events, such as DNA methylation. There have been no studies to elucidate entire genome DNA methylation changes associated… read more here.
Keywords: genome wide; methylation; wide dna; methylation patterns ... See more keywords
Genome-wide DNA methylation profiling of hip articular cartilage identifies differentially methylated loci associated with osteonecrosis of the femoral head.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.06.021
Abstract: OBJECTIVE Recent studies demonstrated a critical role of hip articular cartilage destruction in the development of osteonecrosis of the femoral head (ONFH). The aim of this study was to characterize the genome-wide DNA methylation profile… read more here.
Keywords: genome wide; methylation; zone; wide dna ... See more keywords
Genome-wide DNA methylation changes in two Brassicaceae species sampled alongside a radiation gradient in Chernobyl and Fukushima.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of environmental radioactivity"
DOI: 10.1016/j.jenvrad.2018.07.012
Abstract: The long-term radiological impact to the environment of the nuclear accidents in Chernobyl and Fukushima is still under discussion. In the course of spring of 2016 we sampled two Brassicacea plants, Arabidopsis thaliana and Capsella… read more here.
Keywords: genome wide; methylation; dose rates; wide dna ... See more keywords
Genome-wide DNA methylation analysis of the porcine hypothalamus-pituitary-ovary axis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04603-x
Abstract: Previous studies have suggested that DNA methylation in both CpG and CpH (where H = C, T or A) contexts plays a critical role in biological functions of different tissues. However, the genome-wide DNA methylation patterns of… read more here.
Keywords: genome wide; methylation; hypothalamus pituitary; wide dna ... See more keywords
Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences.
Sign Up to like & getrecommendations! Published in 2021 at "Human reproduction"
DOI: 10.1093/humrep/deab074
Abstract: STUDY QUESTION Do embryos with different developmental competence exhibit different DNA methylation profiles at the blastocyst stage? SUMMARY ANSWER We established genome-wide DNA methylome analysis for embryo trophectoderm (TE) biopsy samples and our findings demonstrated… read more here.
Keywords: genome wide; methylation; methylation profile; wide dna ... See more keywords
Genome‐wide DNA methylation profiling of gastric cardia cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.16054
Abstract: Aberrant DNA methylation has been found in various cancer types including gastric cancer, yet the genome‐wide DNA methylation profile of gastric cardia cancer (GCC) remains unclear. Therefore, we aimed to profile the DNA methylation pattern… read more here.
Keywords: dna; dna methylation; genome wide; wide dna ... See more keywords
Developmental stress does not induce genome-wide DNA methylation changes in wild great tit (Parus major) nestlings.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular ecology"
DOI: 10.1111/mec.16973
Abstract: The environment experienced during early life is a crucial factor in the life of many organisms. This early life environment has been shown to have profound effects on morphology, physiology and fitness. However, the molecular… read more here.
Keywords: methylation; dna methylation; genome wide; wide dna ... See more keywords
Genome-wide DNA methylation profiling in tongue squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14444
Abstract: OBJECTIVES To provide a comprehensive characterization of DNA methylome of oral tongue squamous cell carcinoma (OTSCC) and identify novel tumor-specific DNA methylation markers for early detection using saliva. MATERIAL AND METHODS Genome-wide DNA methylation analysis… read more here.
Keywords: methylation; dna; tongue squamous; dna methylation ... See more keywords
Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021005381
Abstract: Key Points FLT3-ITD and high PRDM16 expression induced methylation changes at STAT5 and AP-1 binding sites in pediatric AML. Hypomethylated regions in PRDM16-highly expressed AMLs were correlated with enhanced chromatin accessibilities at multiple genomic regions. read more here.
Keywords: methylation; methylation analysis; genome wide; dna methylation ... See more keywords