GWAlpha: genome‐wide estimation of additive effects (alpha) based on trait quantile distribution from pool‐sequencing experiments
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btw805
Abstract: Motivation: Sequencing pools of individuals (Pool‐Seq) is a cost‐effective way to gain insight into the genetics of complex traits, but as yet no parametric method has been developed to both test for genetic effects and… read more here.
Keywords: genome wide; wide estimation; pool; additive effects ... See more keywords
GenomegaMap: Within-Species Genome-Wide dN/dS Estimation from over 10,000 Genomes
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msaa069
Abstract: Abstract The dN/dS ratio provides evidence of adaptation or functional constraint in protein-coding genes by quantifying the relative excess or deficit of amino acid-replacing versus silent nucleotide variation. Inexpensive sequencing promises a better understanding of… read more here.
Keywords: species genome; genome wide; wide estimation; within species ... See more keywords