Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity.
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DOI: 10.1242/jcs.258338
Abstract: The toxic metalloid arsenic causes widespread misfolding and aggregation of cellular proteins. How these protein aggregates are formed in vivo, the mechanisms by which they affect cells, and how cells prevent their accumulation is not… read more here.
Keywords: genome wide; aggregation; wide imaging; toxicity ... See more keywords