Genome‐wide interaction studies identify sex‐specific risk alleles for nonsyndromic orofacial clefts
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DOI: 10.1002/gepi.22158
Abstract: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect in humans and is notable for its apparent sexual dimorphism where approximately twice as many males are affected as… read more here.
Keywords: genome wide; risk; sex; studies identify ... See more keywords
Extended methods for gene–environment‐wide interaction scans in studies of admixed individuals with varying degrees of relationships
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22196
Abstract: The etiology of many complex diseases involves both environmental exposures and inherited genetic predisposition as well as interactions between them. Gene–environment‐wide interaction studies (GEWIS) provide a means to identify the interactions between genetic variation and… read more here.
Keywords: varying degrees; degrees relationships; environment wide; interaction ... See more keywords
Genome-wide interaction study of physical activity and genetic susceptibility on colorectal cancer using UK biobank data
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DOI: 10.1038/s41598-025-13709-6
Abstract: Colorectal cancer (CRC) risk is influenced by a complex interplay between genetic predisposition and lifestyle factors, such as physical activity (PA). We aimed to conduct a genome-wide interaction study (GWIS) to explore single nucleotide polymorphisms… read more here.
Keywords: colorectal cancer; interaction study; wide interaction; genome wide ... See more keywords
A review: simulation tools for genome-wide interaction studies.
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DOI: 10.1093/bfgp/elae034
Abstract: Genome-wide association study (GWAS) is essential for investigating the genetic basis of complex diseases; nevertheless, it usually ignores the interaction of multiple single nucleotide polymorphisms (SNPs). Genome-wide interaction studies provide crucial means for exploring complex… read more here.
Keywords: wide interaction; genome wide; simulation; interaction ... See more keywords
Genome-wide interaction study of environmental tobacco smoke exposure on time-to-asthma onset in childhood
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa1278
Abstract: 1Inserm, UMR-946, Genetic Variation and Human Diseases Unit; Université Paris Diderot; Université Pierre et Marie Curie Paris (France), 2Inserm, UMR-946, Genetic Variation and Human Diseases Unit; Université Paris Diderot Paris (France), 3Population Health Sciences, Bristol… read more here.
Keywords: genome wide; interaction study; environmental tobacco; paris ... See more keywords