A Fast and Accurate Method for Genome-Wide Scale Phenome-Wide G × E Analysis and Its Application to UK Biobank.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2019.10.008
Abstract: The etiology of most complex diseases involves genetic variants, environmental factors, and gene-environment interaction (G × E) effects. Compared with marginal genetic association studies, G × E analysis requires more samples and detailed measure of… read more here.
Keywords: genome wide; analysis; wide scale; accurate method ... See more keywords
The structural context of posttranslational modifications at a proteome-wide scale
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DOI: 10.1371/journal.pbio.3001636
Abstract: The recent revolution in computational protein structure prediction provides folding models for entire proteomes, which can now be integrated with large-scale experimental data. Mass spectrometry (MS)-based proteomics has identified and quantified tens of thousands of… read more here.
Keywords: wide scale; modifications proteome; posttranslational modifications; context posttranslational ... See more keywords
Applying a User Centred Design Approach to Optimise a Workplace Initiative for Wide-Scale Implementation
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DOI: 10.3390/ijerph19138096
Abstract: Translation of an effective research intervention into a program able to be implemented in practice typically requires adaptations to ensure the outcomes can be achieved within the applied setting. User centred design (UCD) methodologies can… read more here.
Keywords: wide scale; centred design; user centred; scale implementation ... See more keywords