Widely spaced and divergent inverted repeats become a potent source of chromosomal rearrangements in long single-stranded DNA regions
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DOI: 10.1093/nar/gkad153
Abstract: Abstract DNA inverted repeats (IRs) are widespread across many eukaryotic genomes. Their ability to form stable hairpin/cruciform secondary structures is causative in triggering chromosome instability leading to several human diseases. Distance and sequence divergence between… read more here.
Keywords: single stranded; dna; chromosomal rearrangements; inverted repeats ... See more keywords