Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer cell"
DOI: 10.1016/j.ccell.2018.06.013
Abstract: Hürthle cell carcinoma of the thyroid (HCC) is a form of thyroid cancer recalcitrant to radioiodine therapy that exhibits an accumulation of mitochondria. We performed whole-exome sequencing on a cohort of primary, recurrent, and metastatic… read more here.
Keywords: chromosomal losses; widespread chromosomal; cell carcinoma; cell ... See more keywords
Unique landscape of widespread chromosomal losses in Hürthle cell carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine-related cancer"
DOI: 10.1530/erc-18-0481
Abstract: In their back-to-back published articles "Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes" and "Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle… read more here.
Keywords: chromosomal losses; widespread chromosomal; cell carcinoma; cell ... See more keywords