Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2018.04.019
Abstract: Rare heterozygous coding variants in the triggering receptor expressed in myeloid cells 2 (TREM2) gene, conferring increased risk of developing late-onset Alzheimer's disease, have been identified. We examined the transcriptional consequences of the loss of… read more here.
Keywords: trem2; cell; mouse brain; widespread disruption ... See more keywords