Wild-derived mice: from genetic diversity to variation in immune responses
Sign Up to like & getrecommendations! Published in 2018 at "Mammalian Genome"
DOI: 10.1007/s00335-018-9766-3
Abstract: Classical inbred mouse strains have historically been instrumental in mapping immunological traits. However, most of the classical strains originate from a relatively limited number of founder animals, largely within the Mus musculus domesticus subspecies. Therefore,… read more here.
Keywords: immune; classical inbred; derived mice; diversity ... See more keywords
Wild-derived induced allotetraploids show strong resistance to peanut Early and Late Leaf Spots.
Sign Up to like & getrecommendations! Published in 2022 at "Plant disease"
DOI: 10.1094/pdis-03-22-0721-re
Abstract: Early (ELS) and late leaf spots (LLS) are two of the most destructive diseases in peanut (Arachis hypogaea). They can cause severe plant defoliation and tremendous yield loss in the absence of fungicide applications. The… read more here.
Keywords: induced allotetraploids; late leaf; wild derived; resistance ... See more keywords
Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures
Sign Up to like & getrecommendations! Published in 2024 at "BMC Biology"
DOI: 10.1186/s12915-024-01809-0
Abstract: Social behavior and social organization have major influences on individual health and fitness. Yet, biomedical research focuses on studying a few genotypes under impoverished social conditions. Understanding how lab conditions have modified social organizations of… read more here.
Keywords: field enclosures; biology; female behavior; wild derived ... See more keywords
Novel Neuroprotective Loci Modulating Ischemic Stroke Volume in Wild-Derived Inbred Mouse Strains.
Sign Up to like & getrecommendations! Published in 2019 at "Genetics"
DOI: 10.1534/genetics.119.302555
Abstract: To identify genes involved in cerebral infarction, we have employed a forward genetic approach in inbred mouse strains, using quantitative trait loci (QTL) mapping for cerebral infarct volume after middle cerebral artery occlusion. We had… read more here.
Keywords: volume; eij; wild derived; mouse strains ... See more keywords
1632-P: Wild-Derived Chromosome 1 Substitution Strains—Unveiling Novel Insights into NASH Research
Sign Up to like & getrecommendations! Published in 2024 at "Diabetes"
DOI: 10.2337/db24-1632-p
Abstract: Metabolic diseases, encompassing obesity, NASH, and diabetes, result from a complex interplay of factors, including genetics, lifestyle, and environment. However, conventional mouse models induced by diet or with single genetic alterations often fall short in… read more here.
Keywords: mice; none; wild derived; substitution strains ... See more keywords