CoVSense: Ultrasensitive Nucleocapsid Antigen Immunosensor for Rapid Clinical Detection of Wildtype and Variant SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206615
Abstract: The widespread accessibility of commercial/clinically‐viable electrochemical diagnostic systems for rapid quantification of viral proteins demands translational/preclinical investigations. Here, Covid‐Sense (CoVSense) antigen testing platform; an all‐in‐one electrochemical nano‐immunosensor for sample‐to‐result, self‐validated, and accurate quantification of the… read more here.
Keywords: covsense ultrasensitive; immunosensor; ultrasensitive nucleocapsid; wildtype ... See more keywords
LARGE‐PD: Examining the genetics of Parkinson's disease in Latin America
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.27081
Abstract: Expanded alleles accounted for 74.3% of the observed variability in the age at onset, whereas normal alleles explained a discrete additional 0.5% of the total age at onset variance, and 1.95% of the variance of… read more here.
Keywords: expanded alleles; wildtype; ataxin; genetics ... See more keywords
Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors restores vision in mice
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-019-14181-3
Abstract: Supplementing wildtype copies of functionally defective genes with adeno-associated virus (AAV) is a strategy being explored clinically for various retinal dystrophies. However, the low cargo limit of this vector allows its use in only a… read more here.
Keywords: replacement; aav; wildtype; number photoreceptors ... See more keywords
BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17062-1
Abstract: Isocitrate dehydrogenase 1 (IDH1)-wildtype glioblastoma (GBM) has found to be accompanied with increased expression of branched-chain amino acid trasaminase1 (BCAT1), which is associated with tumor growth and disease progression. In this retrospective study, quantitative RT-PCR, immunohistochemistry,… read more here.
Keywords: bcat1 level; wildtype; idh1 wildtype; wildtype glioblastoma ... See more keywords
INNV-16. COMPLETE RESPONSE OF THALAMIC IDH WILDTYPE GLIOBLASTOMA AFTER PROTON THERAPY FOLLOWED BY CHEMOTHERAPY TOGETHER WITH TUMOR TREATING FIELDS
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.559
Abstract: Proton therapy is able to apply high radiation doses to the tumor while sparing healthy tissues by reducing integral dose. Tumor Treating Fields (TTFields) are low intensity (1–3 V/cm) and intermediate frequency (100–300 kHz) alternating… read more here.
Keywords: proton therapy; idh wildtype; wildtype; response ... See more keywords
Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide in the mouse gut depends on the resident microbiota
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.81212
Abstract: Many microbiota-based therapeutics rely on our ability to introduce a microbe of choice into an already-colonized intestine. In this study, we used genetically barcoded Bacteroides thetaiotaomicron (B. theta) strains to quantify population bottlenecks experienced by… read more here.
Keywords: gut; microbiota; colonization; strain ... See more keywords