BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17062-1
Abstract: Isocitrate dehydrogenase 1 (IDH1)-wildtype glioblastoma (GBM) has found to be accompanied with increased expression of branched-chain amino acid trasaminase1 (BCAT1), which is associated with tumor growth and disease progression. In this retrospective study, quantitative RT-PCR, immunohistochemistry,… read more here.
Keywords: bcat1 level; wildtype; idh1 wildtype; wildtype glioblastoma ... See more keywords
EP14.01 A RARE CNS PRIMARY COLLISION TUMOR IDH-WILDTYPE GLIOBLASTOMA WITH COEXISTENT EPENDYMOMA A CASE REPORT
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf193.632
Abstract: Gliomas arise from glial progenitor cells and constitute a heterogeneous group of tumors. They include mainly glioblastomas, astrocytomas, oligodendrogliomas and ependymomas. IDH-wildtype Glioblastoma are the most common primary CNS malignant tumors. Ependymomas arise from the… read more here.
Keywords: tumor; wildtype; idh wildtype; wildtype glioblastoma ... See more keywords
NF1 expression profiling in IDH-wildtype glioblastoma: genomic associations and survival outcomes
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DOI: 10.1186/s40478-024-01875-z
Abstract: NF1 inactivation is associated with sensitivity to MEK inhibitor targeted therapy in low-grade and some high-grade gliomas. NF1 loss may also be a harbinger of exploitable vulnerabilities in IDH-wildtype glioblastoma (GBM). Accurate and consistent detection… read more here.
Keywords: idh wildtype; antibody; wildtype; wildtype glioblastoma ... See more keywords
Noninvasive prediction of Ki-67 expression level in IDH-wildtype glioblastoma using MRI histogram analysis: comparison and combination of MRI morphological features
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1577816
Abstract: Purpose To assess and compare the effectiveness of magnetic resonance imaging (MRI) morphological features and MRI histogram analysis in noninvasively predicting Ki-67 expression levels in patients with IDH-wildtype glioblastoma. Methods Forty-six cases of IDH-wildtype glioblastoma… read more here.
Keywords: idh wildtype; mri morphological; level; morphological features ... See more keywords