Wilms’ tumour: A review of 15 years recent experience
Sign Up to like & getrecommendations! Published in 2018 at "Anales De Pediatria"
DOI: 10.1016/j.anpede.2017.03.019
Abstract: Abstract Introduction Wilms’ tumour is the most frequent renal tumour in children. Multi-modal treatment includes chemotherapy and surgery, with or without radiotherapy. The survival is excellent, with rates exceeding 90%. A review is presented on… read more here.
Keywords: treatment; review years; tumour review; wilms tumour ... See more keywords
Bilateral Wilms' tumour: An international comparison of treatments and outcomes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2021.01.040
Abstract: INTRODUCTION Wilms' tumour is the most common childhood renal malignancy, with 5-10% of cases presenting bilaterally 1. However, there is currently no consensus between centres on optimal management of bilateral Wilms' tumours. This is an… read more here.
Keywords: outcomes bilateral; income centres; bilateral wilms; low income ... See more keywords
Relationship of tumour-associated macrophages with poor prognosis in Wilms' tumour.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pediatric urology"
DOI: 10.1016/j.jpurol.2020.03.016
Abstract: BACKGROUND Wilms' tumour (WT) is the most common childhood renal tumour. Tumour-associated macrophages (TAMs) are a critical component of tumour microenvironments and contain two main subtypes, classically (M1) or alternatively (M2) activated macrophages. Evidence has… read more here.
Keywords: poor prognosis; stage; relationship; wilms tumour ... See more keywords
New tools for Wilms tumour research
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Urology"
DOI: 10.1038/s41585-019-0252-9
Abstract: respective parental tumours. Histological analysis showed that three spheroid strains comprised mostly blastemal cells, one was primarily epithelial in origin and the other contained mainly immature stromal cells. Spheroids of each type could be successfully… read more here.
Keywords: new tools; wilms tumour; tools wilms; tumour research ... See more keywords
Outcome of two patients with bilateral nephroblastomatosis/Wilms tumour treated with an add-on 13-cis retinoic acid therapy – Case report
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2018.1515284
Abstract: Abstract Although the fate of nephrogenic rests varies, they are known to be precursors of Wilms tumour. Thus, nephrogenic rests require adequate treatment to prevent malignant transformation. We added 13-cis retinoic acid to the standard… read more here.
Keywords: cis retinoic; nephrogenic rests; two patients; retinoic acid ... See more keywords
Pathology of Wilms' tumour in International Society of Paediatric Oncology (SIOP) and Children's oncology group (COG) renal tumour studies: Similarities and differences
Sign Up to like & getrecommendations! Published in 2022 at "Histopathology"
DOI: 10.1111/his.14632
Abstract: Excellent outcomes for patients with Wilms' tumour (WT), >90% for all stages together, have been achieved through researching WT in multicentre and multinational trials and studies in the last 50 years, led by two major groups—the… read more here.
Keywords: oncology; wilms tumour; siop; international society ... See more keywords
Germline mutations and somatic inactivation of TRIM28 in Wilms tumour
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DOI: 10.1371/journal.pgen.1007399
Abstract: Wilms tumour is a childhood tumour that arises as a consequence of somatic and rare germline mutations, the characterisation of which has refined our understanding of nephrogenesis and carcinogenesis. Here we report that germline loss… read more here.
Keywords: inactivation trim28; wilms tumour; germline mutations;
Immune-related gene signature associates with immune landscape and predicts prognosis accurately in patients with Wilms tumour
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.920666
Abstract: Wilms tumour (WT) is the most common kidney malignancy in children. Chemoresistance is the leading cause of tumour recurrence and poses a substantial therapeutic challenge. Increasing evidence has underscored the role of the tumour immune… read more here.
Keywords: wilms tumour; signature; tumour immune; immune landscape ... See more keywords
Spectrum of pediatric kidney tumours with special references to WT1 immunostain at a tertiary care hospital
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_436_19
Abstract: Context or Background: Pediatric renal tumours are the second most common solid tumours in children. The most common in this group is Wilms tumour with mesoblastic nephroma being the 2nd most common tumour in children,… read more here.
Keywords: wt1 immunostain; wilms tumour; care hospital; tertiary care ... See more keywords