The wisdom trial is based on faulty reasoning and has major design and execution problems
Sign Up to like & getrecommendations! Published in 2020 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-020-06020-7
Abstract: To evaluate the design and plan of execution of the “WISDOM” trial. The rationale and reasoning behind the WISDOM Trial were reviewed and analyzed. The published parameters of the trial were reviewed. The study is… read more here.
Keywords: trial; wisdom trial; trial based; based faulty ... See more keywords
Inhaled Corticosteroid Withdrawal and Change in Lung Function in Primary Care Chronic Obstructive Pulmonary Disease Patients in England.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the American Thoracic Society"
DOI: 10.1513/annalsats.202111-1238oc
Abstract: RATIONALE In COPD, inhaled corticosteroids (ICS) are associated with pneumonia highlighting the importance of investigating subgroups of patients who may benefit from prolonged ICS use. Despite this, the WISDOM trial found a greater decline in… read more here.
Keywords: copd; year; copd patients; fev1 decline ... See more keywords